GLPBio

Hydrocortisone buteprate

Catalog No.: GC36267Purity:>99.50%
COASDSData Sheet
Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders.

Products are for research use only. Not for human use. We do not sell to patients.

Hydrocortisone buteprate
Cas No.: 72590-77-3
10mM (in 1mL DMSO)In Stock
$52.00
1
10mgIn Stock
$46.00
1
50mgIn Stock
$139.00
1
100mgIn Stock
$241.00
1
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Description

Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation[1].

[1]. FÖlster-Holst R, et al. Topical hydrocortisone 17-butyrate 21-propionate in the treatment of inflammatory skin diseases: pharmacological data, clinical efficacy, safety and calculation of the therapeutic index. Pharmazie. 2016 Mar;71(3):115-21.

Product Documents

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
72590-77-3
SMILES
CCC(OCC([C@@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C(CC3)=CC(CC4)=O)C)([H])[C@@H](O)C2)([H])CC1)C)OC(CCC)=O)=O)=O
Molecular Formula
C28H40O7
Molecular Weight
488.61
Solubility
DMSO: 250 mg/mL (511.66 mM)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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