GLPBio

Evenamide

Catalog No.: GC38389Purity:>98%Synonyms: NW-3509
COASDSData Sheet
Evenamide (NW-3509) is an orally available voltage-gated sodium channel (VGSC) blocker (Ki=0.4 ?M) for the research of schizophrenia.

Products are for research use only. Not for human use. We do not sell to patients.

Evenamide
Cas No.: 1092977-61-1
10mM (in 1mL DMSO)In Stock
$99.00
1
5mgIn Stock
$90.00
1
10mgIn Stock
$144.00
1
25mgIn Stock
$288.00
1
50mgIn Stock
$459.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Evenamide (NW-3509), a sodium channel blocker, shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness[1].

[1]. Valentina Zuliani, et al. Advances in Design and Development of Sodium Channel Blockers. Ion Channels and Their Inhibitors pp 79-115.

Chemical Properties

CAS No.
1092977-61-1
Synonyms
NW-3509
SMILES
O=C(N(C)C)CNCCC1=CC=CC(OCCCC)=C1
Molecular Formula
C16H26N2O2
Molecular Weight
278.39
Solubility
DMSO: 290 mg/mL (1041.70 mM)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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