GLPBio

Denudatine

Catalog No.: GC38483Purity:>98%
COASDSData Sheet
An alkaloid with antiarrhythmic activities

Products are for research use only. Not for human use. We do not sell to patients.

Denudatine
Cas No.: 26166-37-0
20mgIn Stock
$180.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Denudatine, is primarily isolated from plants of the genera Aconitum and Delphinium[1]. Denudatine has effects on action potential of ventricular fibers and inhibits arrhythmogenic action of aconitine[2].

[1]. Nishiyama Y, et al. Synthesis of Cardiopetaline via a Wagner-Meerwein Rearrangement without Preactivation of the Pivotal Hydroxy Group. Org Lett. 2017 Nov 3;19(21):5833-5835. [2]. Liu TF, et al. Effects of denudatine on action potential of ventricular fibers and its inhibition on arrhythmogenic action of aconitine (author's transl). Zhongguo Yao Li Xue Bao. 1982 Mar;3(1):32-4.

Chemical Properties

CAS No.
26166-37-0
SMILES
O[C@@H]([C@]1([H])CC2)[C@@]3([H])C([C@@]4([H])C5)(CCCC4(C)CN6CC)[C@@]6([H])[C@@]5([H])[C@]32[C@H](O)C1=C
Molecular Formula
C22H33NO2
Molecular Weight
343.5
Solubility
Chloroform: soluble,DMSO: soluble
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

Review for Denudatine

Rating: 5
  • 5 Star100%
  • 4 Star0%
  • 3 Star0%
  • 2 Star0%
  • 1 Star0%