Potassium Hyaluronate from Cockscomb is a large molecule composed of repeated disaccharide units, which is used as a skin conditioner in cosmetics and can penetrate into the dermis layer [1]. Potassium Hyaluronate from Cockscomb has excellent viscoelasticity, high moisture retention capacity, high biocompatibility, and hygroscopic properties, which acts as a lubricant, shock absorber, joint structure stabilizer, and water balance- and flow resistance-regulator [2]. Potassium Hyaluronate from Cockscomb can be used as a drug delivery carrier to safely alter pharmacokinetics and efficiently transport drugs throughout the body[3]. Potassium Hyaluronate from Cockscomb can be utilized to develop artificial tears for promoting the healing of corneal epithelial wounds in mechanical scratch models[4].
References:
[1] Becker L C, Bergfeld W F, Belsito D V, et al. Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate[J]. International journal of toxicology, 2009, 28(4_suppl): 5-67.
[2] Gupta R C, Lall R, Srivastava A, et al. Hyaluronic acid: molecular mechanisms and therapeutic trajectory[J]. Frontiers in veterinary science, 2019, 6: 458280.
[3] Price R D, Berry M G, Navsaria H A. Hyaluronic acid: the scientific and clinical evidence[J]. Journal of Plastic, Reconstructive & Aesthetic Surgery, 2007, 60(10): 1110-1119.
[4] Ho W, Chiang T, Chang S W, et al. Enhanced corneal wound healing with hyaluronic acid and high‐potassium artificial tears[J]. Clinical and Experimental Optometry, 2013, 96(6): 536-541.