Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.
Targets for Endogenous Metabolite
Products for Endogenous Metabolite
- Cat.No. Product Name Information
- GC11282 β-Estradiol Sex hormone
α-Carotene is a precursor of vitamin A that has been found in various fruits and vegetables.
α-Ecdysone is a prohormone of 20-hydroxy ecdysone, an insect-molting, ecdysteroid hormone.
α-Muricholic acid is a murine-specific primary bile acid.
- GC38287 α-Pyridone
- GC63275 β-Cryptoxanthin
D-Glucose, a naturally occurring monosaccharide found in plants, is the primary energy source for living organisms.
- GC40719 β-Muricholic Acid A murine-specific primary bile acid
- GC38010 γ-Aminobutyric acid
- GC63279 γ-Glu-Gly TFA
- GC15975 α-Estradiol Endogenous estrogen receptor ligand
- GC30187 γ-Glu-Phe (γ-Glutamylphenylalanine)
- GC41670 (±)-Epinephrine (hydrochloride) (±)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for α1A-, β2-, and β1-adrenergic receptors, respectively).
- GC38369 (±)-Leucine
- GC39271 (±)-Naringenin
- GC13890 (±)-Palmitoylcarnitine chloride intermediate in mitochondrial fatty acid oxidation
- GC19444 (±)20-HDHA
- GC40442 (±)8-HETE (±)8-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.
- GC30586 (±) Anabasine
- GC61647 (+)-Longifolene
- GC10675 (+,-)-Octopamine HCl adrenoceptor agonist
- GC45245 (-)-Caryophyllene oxide (-)-Caryophyllene oxide is a bicyclic sesquiterpene and a metabolite of β-caryophyllene that has been found in C.
- GC17470 (-)-Cotinine α3/α6β2 nAChR activator
- GC31620 (-)-Fucose (6-Desoxygalactose)
- GC34951 (-)-Menthol
- GC38299 (2-Aminoethyl)phosphonic acid
- GC38265 (2R,3R)-2,3-Dihydroxysuccinic acid
- GC62731 (2R,3R)-Butane-2,3-diol
- GC38296 (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride
- GC33797 (3-Carboxypropyl)trimethylammonium chloride (γ-Butyrobetaine hydrochloride)
- GC38144 (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one
- GC38283 (3S,4S,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one
- GC12395 (D)-(+)-Neopterin Precursor of biopterin synthesis
- GC38684 (E)-m-Coumaric acid
- GC62734 (E)-Oct-2-enoic acid
- GC60404 (Ethoxymethyl)benzene
- GA11210 (H-Cys-OH)2 (H-Cys-OH)2
- GC41721 (R)-α-Lipoic Acid (R)-α-Lipoic acid is the naturally occurring enantiomer of lipoic acid, a cyclic disulfide antioxidant.
- GC34442 (R)-(+)-Citronellal
- GC38262 (R)-(-)-1,3-Butanediol
- GC30210 (R)-3-Hydroxybutanoic acid
- GC61759 (R)-3-Hydroxybutanoic acid sodium
- GC30661 (R)-3-Hydroxyisobutyric acid
- GC38282 (R)-5-Oxopyrrolidine-2-carboxylic acid
- GC38364 (R)-Ornithine hydrochloride
- GC38363 (R)-pyrrolidine-2-carboxylic acid
- GC39832 (R,R)-(+)-Hydrobenzoin
- GC39833 (S)-(+)-1,2-Propanediol
- GC62747 (S)-(-)-Citronellal
- GC38371 (S)-(-)-Phenylethanol
- GC62748 (S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate
- GC31630 (S)-2-Hydroxy-3-phenylpropanoic acid
- GC31622 (S)-2-Hydroxysuccinic acid
- GC30649 (S)-3,4-Dihydroxybutyric acid
- GC62749 (S)-3-Hydroxy-2-(Phosphonooxy)Propanoic Acid
- GC30304 (S)-3-Hydroxybutanoic acid ((S)-β-Hydroxybutanoic acid)
- GC30623 (S)-3-Hydroxyisobutyric acid
- GC30148 (S)-b-aminoisobutyric acid
- GC62751 (S)-Higenamine hydrobromide
- GC30735 (S)-Leucic acid
- GC35003 (S)-Nornicotine
- GC31253 (Z)-Hexadec-9-enoic acid
- GC16375 (±)-Jasmonic Acid methyl ester Suppresses proliferation and induces apoptosis
- GC41765 1,2,3-Tri-13(Z)-Docosenoyl-rac-glycerol 1,2,3-Tri-13(Z)-docosenoyl-rac-glycerol is a triacylglycerol that contains 13(Z)-docosenoic acid at the sn-1, sn-2, and sn-3 positions and has been found in nasturtium seed oil.
- GC41767 1,2,3-Triarachidonoyl-rac-glycerol Triarachidin is a triacylglycerol containing three arachidic acid groups.
- GC41768 1,2,3-Tridecanoyl-rac-glycerol 1,2,3-Tridecanoyl-rac-glycerol is a triacylglycerol that contains decanoic acid at the sn-1, sn-2, and sn-3 positions.
- GC46041 1,2,3-Trilinoleoyl-rac-glycerol
- GC41774 1,2,3-Trimyristoyl-rac-glycerol Trimyristin is a triacylglycerol of myristic acid that is found in nutmeg.
- GC41778 1,2,3-Tripalmitoyl-rac-glycerol 1,2,3-Tripalmitoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1, sn-2, and sn-3 positions and has been found in palm oil.
- GC39766 1,2-Cyclohexanedione
- GC41804 1,2-Dimyristoyl-sn-glycero-3-PE Phosphatidylethanolamines (PEs) are phospholipids found in biological membranes, serving both structural and functional roles.
- GC41822 1,2-Dipalmitoyl-sn-glycero-3-PE 1,2-Dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) is a naturally-occurring PE containing 16:0 fatty acids at the sn-1 and sn-2 positions.
- GC41825 1,2-Dipalmitoyl-sn-glycero-3-phosphate (sodium salt) Phosphatidic acids can be formed by the acylation of lysophosphatidic acids, the phosphorylation of diacylglycerols, or the removal of the choline group from phosphatidylcholine.
weak activator of PKC
- GC33621 1,2-Dipalmitoyl-sn-glycerol 3-phosphate
- GC33789 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (1,2-DSPE)
- GC62352 1,3-Butanediol
- GC60433 1,3-Dimethyluracil
- GC30749 1,3-Dimethyluric acid
- GC60011 1,3-Dithiane
- GC62755 1,4-D-Gulonolactone
- GC35039 1,4-Diaminobutane dihydrochloride
- GC60435 1,4-Dimethoxybenzene
- GC38242 1,4-Dioxane-2,5-diol
- GC33801 1,5-Anhydrosorbitol
- GC19717 1,6-anhydroglucose
- GC38270 1-Aminocyclopropane-1-carboxylic acid
- GC35029 1-Arachidoyl-sn-glycero-3-phosphocholine
- GC60445 1-Dodecanol
- GC17829 1-Hexadecanol Fatty alcohol
- GC38271 1-Hydroxy-2-naphthoic acid
- GC38670 1-Hydroxyoctadecane
- GC60448 1-Hydroxypyrene
- GC32294 1-Kestose
- GC33646 1-Methyladenine
- GC33463 1-Methyladenosine
- GC61442 1-Methylguanidine hydrochloride
- GC35067 1-Methylguanosine
1-Methylhistamine is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism.
- GC42000 1-Methylnicotinamide (chloride) Nicotinamide is a precursor of NAD and NADP, which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events.