GPCR19

GPCR19 is a G protein-coupled receptor for bile acid. Activation of this receptor induces its internalization and the production of intreacelluar cAMP. It is Involved in the suppression of macrophage function and regulation of energy homeostasis.

Products Related to GPCR19(12)

GC16363 TGR5 Receptor Agonist
CAS: 1197300-24-5
Purity: >99.50%
TGR5 G-protein receptor agonist
GC30565 BAR502
CAS: 1612191-86-2
Purity: >98.00%
A dual agonist of GP-BAR1 and FXR
GC31370 SB756050
CAS: 447410-57-3
Purity: >99.00%
A TGR5 agonist
GC32742 INT-767
CAS: 1000403-03-1
Purity: >98.00%
INT-767 is a potent dual agonist of the farnesoid X receptor (FXR) and the Takeda G protein-coupled receptor 5 (TGR5), with EC 50 values of 30nM and 630nM, respectively.
GC33762 Deoxycholic acid (Cholanoic Acid)
CAS: 83-44-3
Purity: >98.00%
Deoxycholic acid (Cholanoic Acid) is a bile acid and a byproduct of intestinal metabolism that can activate the G protein-coupled bile acid receptor TGR5.
GC33768 Deoxycholic acid sodium salt (Sodium deoxycholate)
CAS: 302-95-4
Purity: >99.00%
Deoxycholic acid sodium salt (Sodium deoxycholate) is a bile acid that is a byproduct of intestinal metabolism and can activate the G protein-coupled bile acid receptor TGR5.
GC34775 SBI-115
CAS: 882366-16-7
Purity: >98.00%
SBI-115 is an antagonist of the G protein-coupled bile acid receptor 1 (TGR5; GPCR19).
GC36319 INT-777 R-enantiomer
CAS: 1198786-98-9
Purity: >98%
INT-777 R-enantiomer is the R-enantiomer of INT-777, with EC50 of 4.79 μM for TGR5, and less potent than INT-777.
GC40637 BAR501
CAS: 1632118-69-4
Purity: >98.00%
BAR501 is a selective agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1; EC50 = 1 μM) that lacks activity at the farnesoid X receptor (FXR).
GC46012 DY 268
CAS: 1609564-75-1
Purity: >98.00%
DY 268 is apotent farnesoid X receptor (FXR) antagonist with an IC 50 value of 7.5nM.
GN10489 Hyodeoxycholic acid
CAS: 83-49-8
Purity: >99.00%
GC13681 INT-777
CAS: 1199796-29-6
Purity: >98.00%
INT-777 is a selective TGR5 agonist with an EC 50 of 0.82μM.

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC16363	TGR5 Receptor Agonist	1197300-24-5	>99.50%
GC16363	TGR5 G-protein receptor agonist
GC30565	BAR502	1612191-86-2	>98.00%
GC30565	A dual agonist of GP-BAR1 and FXR
GC31370	SB756050	447410-57-3	>99.00%
GC31370	A TGR5 agonist
GC32742	INT-767	1000403-03-1	>98.00%
GC32742	INT-767 is a potent dual agonist of the farnesoid X receptor (FXR) and the Takeda G protein-coupled receptor 5 (TGR5), with EC 50 values of 30nM and 630nM, respectively.
GC33762	Deoxycholic acid (Cholanoic Acid)	83-44-3	>98.00%
GC33762	Deoxycholic acid (Cholanoic Acid) is a bile acid and a byproduct of intestinal metabolism that can activate the G protein-coupled bile acid receptor TGR5.
GC33768	Deoxycholic acid sodium salt (Sodium deoxycholate)	302-95-4	>99.00%
GC33768	Deoxycholic acid sodium salt (Sodium deoxycholate) is a bile acid that is a byproduct of intestinal metabolism and can activate the G protein-coupled bile acid receptor TGR5.
GC34775	SBI-115	882366-16-7	>98.00%
GC34775	SBI-115 is an antagonist of the G protein-coupled bile acid receptor 1 (TGR5; GPCR19).
GC36319	INT-777 R-enantiomer	1198786-98-9	>98%
GC36319	INT-777 R-enantiomer is the R-enantiomer of INT-777, with EC50 of 4.79 μM for TGR5, and less potent than INT-777.
GC40637	BAR501	1632118-69-4	>98.00%
GC40637	BAR501 is a selective agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1; EC50 = 1 μM) that lacks activity at the farnesoid X receptor (FXR).
GC46012	DY 268	1609564-75-1	>98.00%
GC46012	DY 268 is apotent farnesoid X receptor (FXR) antagonist with an IC 50 value of 7.5nM.
GN10489	Hyodeoxycholic acid	83-49-8	>99.00%
GC13681	INT-777	1199796-29-6	>98.00%
GC13681	INT-777 is a selective TGR5 agonist with an EC 50 of 0.82μM.