GLPBio

Gutathione S-transferase

GSTs (Glutathione s-transferases)is a detoxification enzyme that catalyze the binding of electrophilic substrates to glutathione. They involved in removal of ROS, inhibition of Jun kinase and can conjugate non-catalytically to various ligands.

Products Related to Gutathione S-transferase(12)

  • GC13409 structure
    GC13409Ezatiostat hydrochloride
    CAS: 286942-97-0
    Purity: >98%

    GST inhibitor

  • GC10519 structure
    GC10519Ethacrynic acid - d5
    CAS: 1330052-59-9
    Purity: >98%

    Used as an internal standard for GC- or LC-mass spectrometry

  • GC17287 structure
    GC17287Iberin
    CAS: 505-44-2
    Purity: >98.00%

    induces the expression of phase II detoxification enzymes, including quinone reductase and glutathione S-transferase

  • GC30647 structure
    GC30647TLK117 (TER117)
    CAS: 152684-53-2
    Purity: >99.50%
  • GC32971 structure
    GC32971GSTO1-IN-1
    CAS: 568544-03-6
    Purity: >99.00%

    GSTO1-IN-1 is a potent glutathione S-transferase omega 1 (GSTO1) inhibitor with an IC50 of 31 nM.

  • GC33342 structure
    GC33342GSTO-IN-2
    CAS: 1202710-57-3
    Purity: >98.00%

    GSTO-IN-2 is a glutathione S-transferase inhibitor with IC50s of 3.6, 16.3, and 1.4 μM for GSTA2, GSTM1, and GSTP1-1.

  • GC35727 structure
    GC35727Coniferyl ferulate
    CAS: 63644-62-2
    Purity: >98.50%

    A monolignal conjugate with diverse biological activities

  • GC35759 structure
    GC35759Curzerene
    CAS: 17910-09-7
    Purity: >95.00%

    Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis.

  • GC44882 structure
    GC44882Seneciphylline
    CAS: 480-81-9
    Purity: >99.50%

    Seneciphylline is an alkaloid that has been found F.

  • GC63518 structure
    GC63518LAS17
    CAS: 2362527-67-9
    Purity: >98%

    LAS17 is a potent and selective tyrosine-directed irreversible inhibitor for glutathione?S-Transferase Pi (GSTP1) . LAS17 inhibits GSTP1 activity with an IC50 of 0.5 ?M.

  • GC64919 structure
    GC64919AZD9898
    CAS: 2042347-69-1
    Purity: >98%

    AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM.

  • GC65438 structure
    GC65438TK05
    CAS: 1245734-61-5
    Purity: >98%

    TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM.