GLPBio

HR68

Catalog No.: GC91403Purity:>98.00%Synonyms: PP21
HR68 is an anticancer agent and a derivative of the peroxisome proliferator-activated receptor (PPAR) agonist fenofibric acid .

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HR68
Cas No.: 2454582-64-8
1mgIn Stock
$35.00
1
5mgIn Stock
$124.00
1
10mgIn Stock
$210.00
1
50mgIn Stock
$788.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

HR68 is an anticancer agent and a derivative of the peroxisome proliferator-activated receptor (PPAR) agonist fenofibric acid .1 It decreases the viability of LN-229 glioblastoma cells (IC50 = 1.17 µM). HR68 crosses the blood-brain barrier in a temozolomide-resistant orthotopic patient-derived xenograft (PDX) mouse model of glioblastoma.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
2454582-64-8
Synonyms
PP21
Molecular Formula
C22H19ClN2O3
Molecular Weight
394.9
Solubility
Acetonitrile: Soluble,Chloroform: Soluble,Methanol: Soluble
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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