HR68 is an anticancer agent and a derivative of the peroxisome proliferator-activated receptor (PPAR) agonist fenofibric acid .1 It decreases the viability of LN-229 glioblastoma cells (IC50 = 1.17 µM). HR68 crosses the blood-brain barrier in a temozolomide-resistant orthotopic patient-derived xenograft (PDX) mouse model of glioblastoma.
Citations
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Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
2454582-64-8
Synonyms
PP21
Molecular Formula
C22H19ClN2O3
Molecular Weight
394.9
Solubility
Acetonitrile: Soluble,Chloroform: Soluble,Methanol: Soluble
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
Reviews
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