Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor ( IC50: 46 and 15 nM) [1].
References:
[1]. Maillard MC, et al. Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19(19):5833-51.
References:
[1]. Maillard MC, et al. Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19(19):5833-51.