Pitavastatin Calcium (Synonyms: Itabastatin, Itavastatin, NKS 104) |
| カタログ番号GC12116 |
ピタバスタチン カルシウム (NK-104 ヘミカルシウム) は、強力なヒドロキシメチルグルタリル CoA (HMG-CoA) レダクターゼ阻害剤です。
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Cas No.: 147526-32-7
Sample solution is provided at 25 µL, 10mM.
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Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.
Review for Pitavastatin Calcium
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
Review for Pitavastatin Calcium
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