Prunin (Synonyms: Naringenin 7-O-β-D-glucopyranoside, Naringenin 7-O-glucoside, NSC 135064) |
| カタログ番号GC39066 |
プルニンは、ヒト エンテロ ウイルス A71 (HEVA71) の強力な阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 529-55-5
Sample solution is provided at 25 µL, 10mM.
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Prunin is a potent inhibitor of human enterovirus A71 (HEVA71). Prunin shows strong inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), with an IC50 of 5.5 µM[1][2].
[1]. Gunaseelan S, et al. Prunin suppresses viral IRES activity and is a potential candidate for treating enterovirus A71 infection. Sci Transl Med. 2019 Oct 30;11(516). pii: eaar5759. [2]. Jung HA, et al. Prunin is a highly potent flavonoid from Prunus davidiana stems that inhibits protein tyrosine phosphatase 1B and stimulates glucose uptake in insulin-resistant HepG2 cells. Arch Pharm Res. 2017 Jan;40(1):37-48.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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