PY109 is an orally active and highly selective aryl hydrocarbon receptor ( AHR ) agonist. PY109's EC 50 values in human-derived HepG2 and mouse Hepa-1c1c7 cells are 1.2 nM and 1.4 nM respectively. PY109 significantly upregulates the expression of CYP1A1 and IL-22, and inhibits the expression of IL-17A. PY109 significantly improves colitis in mice. PY109 can be used for research on colitis [1].
PY109
Catalog No.: GC79393Purity:>99.00%
PY109 is an orally active and highly selective aryl hydrocarbon receptor ( AHR ) agonist.
製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。
Cas No.: 2378039-23-5
10mM (in 1mL DMSO)In Stock
$32.00
1
5mgIn Stock
$29.00
1
10mgIn Stock
$45.00
1
25mgIn Stock
$79.00
1
50mgIn Stock
$123.00
1
100mgIn Stock
$194.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $32.00 | In Stock | 1 | |
| 5mg | $29.00 | In Stock | 1 | |
| 10mg | $45.00 | In Stock | 1 | |
| 25mg | $79.00 | In Stock | 1 | |
| 50mg | $123.00 | In Stock | 1 | |
| 100mg | $194.00 | In Stock | 1 |
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引用文献 (Citations)
現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
製品説明 (Description)
製品資料 (Product Documents)
Purity:>99.00%Appearance:A solid
化学的性質 (Chemical Properties)
CAS番号
2378039-23-5
分子式
C15H9F3N2O
分子量
290.24
溶解性
DMSO: 100 mg/mL (344.54 mM; Need ultrasonic)
保存条件
Store at -20°C
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。
計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度
g/mol
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