PROTAC Linker
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The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.
Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.
Products Related to PROTAC Linker(1975)
- GC81245tert-Butyl (2-(2-iodoethoxy)ethyl)carbamateCAS: 629626-40-0Purity: >97.00%
tert-Butyl (2-(2-iodoethoxy)ethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC812462-((tert-Butoxycarbonyl)amino)ethyl 4-methylbenzenesulfonateCAS: 158690-56-3Purity: >99.50%
2-((tert-Butoxycarbonyl)amino)ethyl 4-methylbenzenesulfonate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81247Propargyl-PEG4-sulfonic acid sodiumPurity: >98.00%
Propargyl-PEG4-sulfonic acid sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- GC8124812-(Benzyloxy)-12-oxododecanoic acidCAS: 88353-04-2Purity: >98.00%
12-(Benzyloxy)-12-oxododecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81249Cbz-PEG3-prop-1-yneCAS: 2680691-32-9Purity: >98.00%
Cbz-PEG3-prop-1-yne is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81250Benzyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalic acidCAS: 1893054-22-2Purity: >98%
Benzyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC812511,4-Bis(2-bromoethoxy)benzeneCAS: 5471-84-1Purity: >98.00%
1,4-Bis(2-bromoethoxy)benzene is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81252(9H-Fluoren-9-yl)methyl (5-hydroxypentyl)carbamateCAS: 209115-33-3Purity: >98.00%
(9H-Fluoren-9-yl)methyl (5-hydroxypentyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81253PEG4-NH-CbzCAS: 206265-31-8Purity: >98.00%
PEG4-NH-Cbz is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81254Boc-PEG3-mesylateCAS: 430430-57-2Purity: >98.00%
Boc-PEG3-mesylate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC8125515-(tert-Butoxy)-15-oxopentadecanoic acidCAS: 905302-42-3Purity: >98.00%
15-(tert-Butoxy)-15-oxopentadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC812563-((tert-Butoxycarbonyl)amino)propyl 4-methylbenzenesulfonateCAS: 80909-96-2Purity: >98.00%
3-((tert-Butoxycarbonyl)amino)propyl 4-methylbenzenesulfonate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81257Boc-C-PEG2-ICAS: 2338824-60-3Purity: >98.00%
Boc-C-PEG2-I is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81258tert-Butyl (10-bromodecyl)carbamateCAS: 887353-29-9Purity: >98.00%
tert-Butyl (10-bromodecyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81259Tert-butyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridin-1-yl]propanoateCAS: 1802892-92-7Purity: >98%
Tert-butyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridin-1-yl]propanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81260Cl-C6-PEG3-C3-acidCAS: 1835705-78-6Purity: >99.50%
Cl-C6-PEG3-C3-acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC812611,13-DibromotridecaneCAS: 31772-05-1Purity: >98.00%
1,13-Dibromotridecane is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81262Docosane-1,22-diolCAS: 22513-81-1Purity: >98.00%
Docosane-1,22-diol is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC8126314-((tert-Butoxycarbonyl)amino)tetradecanoic acidCAS: 2307778-46-5Purity: >98%
14-((tert-Butoxycarbonyl)amino)tetradecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81264Boc-PEG2-ICAS: 1938057-43-2Purity: >98.00%
Boc-PEG2-I is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81265Tert-butyl methyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)carbamateCAS: 936728-17-5Purity: >98.00%
Tert-butyl methyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81266tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)carbamateCAS: 360792-43-4Purity: >98.00%
tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC812673-(4-((1-(Tert-butoxycarbonyl)piperidin-4-yl)oxy)phenyl)propanoic acidCAS: 1080421-71-1Purity: >98.00%
3-(4-((1-(Tert-butoxycarbonyl)piperidin-4-yl)oxy)phenyl)propanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81268tert-Butyl (11-bromoundecyl)carbamateCAS: 463930-53-2Purity: >98.00%
tert-Butyl (11-bromoundecyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81245 | tert-Butyl (2-(2-iodoethoxy)ethyl)carbamate | 629626-40-0 | >97.00% | |
tert-Butyl (2-(2-iodoethoxy)ethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81246 | 2-((tert-Butoxycarbonyl)amino)ethyl 4-methylbenzenesulfonate | 158690-56-3 | >99.50% | |
2-((tert-Butoxycarbonyl)amino)ethyl 4-methylbenzenesulfonate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81247 | Propargyl-PEG4-sulfonic acid sodium | - | >98.00% | |
Propargyl-PEG4-sulfonic acid sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81248 | 12-(Benzyloxy)-12-oxododecanoic acid | 88353-04-2 | >98.00% | |
12-(Benzyloxy)-12-oxododecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81249 | Cbz-PEG3-prop-1-yne | 2680691-32-9 | >98.00% | |
Cbz-PEG3-prop-1-yne is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81250 | Benzyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalic acid | 1893054-22-2 | >98% | |
Benzyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81251 | 1,4-Bis(2-bromoethoxy)benzene | 5471-84-1 | >98.00% | |
1,4-Bis(2-bromoethoxy)benzene is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81252 | (9H-Fluoren-9-yl)methyl (5-hydroxypentyl)carbamate | 209115-33-3 | >98.00% | |
(9H-Fluoren-9-yl)methyl (5-hydroxypentyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81253 | PEG4-NH-Cbz | 206265-31-8 | >98.00% | |
PEG4-NH-Cbz is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81254 | Boc-PEG3-mesylate | 430430-57-2 | >98.00% | |
Boc-PEG3-mesylate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81255 | 15-(tert-Butoxy)-15-oxopentadecanoic acid | 905302-42-3 | >98.00% | |
15-(tert-Butoxy)-15-oxopentadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81256 | 3-((tert-Butoxycarbonyl)amino)propyl 4-methylbenzenesulfonate | 80909-96-2 | >98.00% | |
3-((tert-Butoxycarbonyl)amino)propyl 4-methylbenzenesulfonate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81257 | Boc-C-PEG2-I | 2338824-60-3 | >98.00% | |
Boc-C-PEG2-I is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81258 | tert-Butyl (10-bromodecyl)carbamate | 887353-29-9 | >98.00% | |
tert-Butyl (10-bromodecyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81259 | Tert-butyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridin-1-yl]propanoate | 1802892-92-7 | >98% | |
Tert-butyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridin-1-yl]propanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81260 | Cl-C6-PEG3-C3-acid | 1835705-78-6 | >99.50% | |
Cl-C6-PEG3-C3-acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81261 | 1,13-Dibromotridecane | 31772-05-1 | >98.00% | |
1,13-Dibromotridecane is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81262 | Docosane-1,22-diol | 22513-81-1 | >98.00% | |
Docosane-1,22-diol is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81263 | 14-((tert-Butoxycarbonyl)amino)tetradecanoic acid | 2307778-46-5 | >98% | |
14-((tert-Butoxycarbonyl)amino)tetradecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81264 | Boc-PEG2-I | 1938057-43-2 | >98.00% | |
Boc-PEG2-I is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81265 | Tert-butyl methyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)carbamate | 936728-17-5 | >98.00% | |
Tert-butyl methyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81266 | tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)carbamate | 360792-43-4 | >98.00% | |
tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81267 | 3-(4-((1-(Tert-butoxycarbonyl)piperidin-4-yl)oxy)phenyl)propanoic acid | 1080421-71-1 | >98.00% | |
3-(4-((1-(Tert-butoxycarbonyl)piperidin-4-yl)oxy)phenyl)propanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81268 | tert-Butyl (11-bromoundecyl)carbamate | 463930-53-2 | >98.00% | |
tert-Butyl (11-bromoundecyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
