PROTAC Linker
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The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.
Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.
Products Related to PROTAC Linker(1988)
- GC81232Propargyl-PEG3-NH-BocCAS: 2222039-38-3Purity: >98.00%
Propargyl-PEG3-NH-Boc is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81233N,N'-(Ethane-1,2-diyl)bis(2-bromoacetamide)CAS: 4960-81-0Purity: >95.00%
N,N'-(Ethane-1,2-diyl)bis(2-bromoacetamide) is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81234tert-Butyl 2-bromo-7-azaspiro[3.5]nonane-7-carboxylateCAS: 1225276-07-2Purity: >98.00%
tert-Butyl 2-bromo-7-azaspiro[3.5]nonane-7-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81235BnO-PEG2-BrCAS: 121537-55-1Purity: >98.00%
BnO-PEG2-Br is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81236Tert-butyl 4-(4-(hydroxymethyl)benzyl)piperazine-1-carboxylateCAS: 622381-67-3Purity: >98.00%
Tert-butyl 4-(4-(hydroxymethyl)benzyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81237Methyl 13-bromotridecanoateCAS: 80982-86-1Purity: >98.00%
Methyl 13-bromotridecanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81239tert-Butyl (8-bromooctyl)carbamateCAS: 142356-35-2Purity: >95.00%
tert-Butyl (8-bromooctyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81240tert-Butyl 7-iodoheptanoateCAS: 54005-76-4Purity: >98.00%
tert-Butyl 7-iodoheptanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81241tert-Butyl (5-iodopentyl)carbamateCAS: 262278-05-7Purity: >98.00%
tert-Butyl (5-iodopentyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81242tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate hydrochlorideCAS: 193902-64-6Purity: >98.00%
tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81243Icosane-1,20-diolCAS: 7735-43-5Purity: >98.00%
Icosane-1,20-diol (1,20-Eicosanediol) is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC8124419-Hydroxynonadecanoic acidCAS: 22438-61-5Purity: >98.00%
19-Hydroxynonadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81245tert-Butyl (2-(2-iodoethoxy)ethyl)carbamateCAS: 629626-40-0Purity: >97.00%
tert-Butyl (2-(2-iodoethoxy)ethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC812462-((tert-Butoxycarbonyl)amino)ethyl 4-methylbenzenesulfonateCAS: 158690-56-3Purity: >99.50%
2-((tert-Butoxycarbonyl)amino)ethyl 4-methylbenzenesulfonate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81247Propargyl-PEG4-sulfonic acid sodiumPurity: >98.00%
Propargyl-PEG4-sulfonic acid sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- GC8124812-(Benzyloxy)-12-oxododecanoic acidCAS: 88353-04-2Purity: >98.00%
12-(Benzyloxy)-12-oxododecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81249Cbz-PEG3-prop-1-yneCAS: 2680691-32-9Purity: >98.00%
Cbz-PEG3-prop-1-yne is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81250Benzyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalic acidCAS: 1893054-22-2Purity: >98%
Benzyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC812511,4-Bis(2-bromoethoxy)benzeneCAS: 5471-84-1Purity: >98.00%
1,4-Bis(2-bromoethoxy)benzene is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81252(9H-Fluoren-9-yl)methyl (5-hydroxypentyl)carbamateCAS: 209115-33-3Purity: >98.00%
(9H-Fluoren-9-yl)methyl (5-hydroxypentyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81253PEG4-NH-CbzCAS: 206265-31-8Purity: >98.00%
PEG4-NH-Cbz is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81254Boc-PEG3-mesylateCAS: 430430-57-2Purity: >98.00%
Boc-PEG3-mesylate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC8125515-(tert-Butoxy)-15-oxopentadecanoic acidCAS: 905302-42-3Purity: >98.00%
15-(tert-Butoxy)-15-oxopentadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81232 | Propargyl-PEG3-NH-Boc | 2222039-38-3 | >98.00% | |
Propargyl-PEG3-NH-Boc is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81233 | N,N'-(Ethane-1,2-diyl)bis(2-bromoacetamide) | 4960-81-0 | >95.00% | |
N,N'-(Ethane-1,2-diyl)bis(2-bromoacetamide) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81234 | tert-Butyl 2-bromo-7-azaspiro[3.5]nonane-7-carboxylate | 1225276-07-2 | >98.00% | |
tert-Butyl 2-bromo-7-azaspiro[3.5]nonane-7-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81235 | BnO-PEG2-Br | 121537-55-1 | >98.00% | |
BnO-PEG2-Br is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81236 | Tert-butyl 4-(4-(hydroxymethyl)benzyl)piperazine-1-carboxylate | 622381-67-3 | >98.00% | |
Tert-butyl 4-(4-(hydroxymethyl)benzyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81237 | Methyl 13-bromotridecanoate | 80982-86-1 | >98.00% | |
Methyl 13-bromotridecanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81238 | Boc-C9-Br | 1644575-06-3 | >98.00% | |
Boc-C9-Br is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81239 | tert-Butyl (8-bromooctyl)carbamate | 142356-35-2 | >95.00% | |
tert-Butyl (8-bromooctyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81240 | tert-Butyl 7-iodoheptanoate | 54005-76-4 | >98.00% | |
tert-Butyl 7-iodoheptanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81241 | tert-Butyl (5-iodopentyl)carbamate | 262278-05-7 | >98.00% | |
tert-Butyl (5-iodopentyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81242 | tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate hydrochloride | 193902-64-6 | >98.00% | |
tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81243 | Icosane-1,20-diol | 7735-43-5 | >98.00% | |
Icosane-1,20-diol (1,20-Eicosanediol) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81244 | 19-Hydroxynonadecanoic acid | 22438-61-5 | >98.00% | |
19-Hydroxynonadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81245 | tert-Butyl (2-(2-iodoethoxy)ethyl)carbamate | 629626-40-0 | >97.00% | |
tert-Butyl (2-(2-iodoethoxy)ethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81246 | 2-((tert-Butoxycarbonyl)amino)ethyl 4-methylbenzenesulfonate | 158690-56-3 | >99.50% | |
2-((tert-Butoxycarbonyl)amino)ethyl 4-methylbenzenesulfonate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81247 | Propargyl-PEG4-sulfonic acid sodium | - | >98.00% | |
Propargyl-PEG4-sulfonic acid sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81248 | 12-(Benzyloxy)-12-oxododecanoic acid | 88353-04-2 | >98.00% | |
12-(Benzyloxy)-12-oxododecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81249 | Cbz-PEG3-prop-1-yne | 2680691-32-9 | >98.00% | |
Cbz-PEG3-prop-1-yne is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81250 | Benzyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalic acid | 1893054-22-2 | >98% | |
Benzyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81251 | 1,4-Bis(2-bromoethoxy)benzene | 5471-84-1 | >98.00% | |
1,4-Bis(2-bromoethoxy)benzene is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81252 | (9H-Fluoren-9-yl)methyl (5-hydroxypentyl)carbamate | 209115-33-3 | >98.00% | |
(9H-Fluoren-9-yl)methyl (5-hydroxypentyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81253 | PEG4-NH-Cbz | 206265-31-8 | >98.00% | |
PEG4-NH-Cbz is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81254 | Boc-PEG3-mesylate | 430430-57-2 | >98.00% | |
Boc-PEG3-mesylate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81255 | 15-(tert-Butoxy)-15-oxopentadecanoic acid | 905302-42-3 | >98.00% | |
15-(tert-Butoxy)-15-oxopentadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||