PROTAC Linker
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The PROTAC linker connects two moieties: a small peptide residue for E3 ubiquitin ligase recognition,and a ligand that can be recognized by a targeted protein.
Unlike the small molecule ligands, the length of the linker has been randomly selected for PROTACs, varying from 12-carbon to over 20-carbon in length. An optimal linker will allow for maximal interaction between the two moieties (target protein and E3 ligase) resulting in efficient ubiquitination of the target protein and its ultimate degradation.
Products Related to PROTAC Linker(2010)
- GC81258tert-Butyl (10-bromodecyl)carbamateCAS: 887353-29-9Purity: >98.00%
tert-Butyl (10-bromodecyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81259Tert-butyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridin-1-yl]propanoateCAS: 1802892-92-7Purity: >98.00%
Tert-butyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridin-1-yl]propanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81260Cl-C6-PEG3-C3-acidCAS: 1835705-78-6Purity: >99.50%
Cl-C6-PEG3-C3-acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC812611,13-DibromotridecaneCAS: 31772-05-1Purity: >98.00%
1,13-Dibromotridecane is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81262Docosane-1,22-diolCAS: 22513-81-1Purity: >98.00%
Docosane-1,22-diol is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC8126314-((tert-Butoxycarbonyl)amino)tetradecanoic acidCAS: 2307778-46-5Purity: >98.00%
14-((tert-Butoxycarbonyl)amino)tetradecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81264Boc-PEG2-ICAS: 1938057-43-2Purity: >98.00%
Boc-PEG2-I is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81265Tert-butyl methyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)carbamateCAS: 936728-17-5Purity: >98.00%
Tert-butyl methyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81266tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)carbamateCAS: 360792-43-4Purity: >98.00%
tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC812673-(4-((1-(Tert-butoxycarbonyl)piperidin-4-yl)oxy)phenyl)propanoic acidCAS: 1080421-71-1Purity: >98.00%
3-(4-((1-(Tert-butoxycarbonyl)piperidin-4-yl)oxy)phenyl)propanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81268tert-Butyl (11-bromoundecyl)carbamateCAS: 463930-53-2Purity: >98.00%
tert-Butyl (11-bromoundecyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81269tert-Butyl (8-iodooctyl)carbamateCAS: 2011713-75-8Purity: >98.00%
tert-Butyl (8-iodooctyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81270Boc-C15-COOHCAS: 905302-44-5Purity: >98.00%
Boc-C15-COOH is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC812711,14-DibromotetradecaneCAS: 37688-96-3Purity: >97.00%
1,14-Dibromotetradecane is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81272Henicosanedioic acidCAS: 505-55-5Purity: >98.00%
Henicosanedioic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC812731,15-DibromopentadecaneCAS: 81726-81-0Purity: >98.00%
1,15-Dibromopentadecane is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC8127416-((tert-Butoxycarbonyl)amino)hexadecanoic acidCAS: 135747-73-8Purity: >98.00%
16-((tert-Butoxycarbonyl)amino)hexadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81275Boc-C14-BrCAS: 905302-64-9Purity: >98.00%
Boc-C14-Br is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81276N3-PEG5-C6-ClCAS: 1261238-21-4Purity: >99.50%
N3-PEG5-C6-Cl is a PEG PROTAC linker, can be used for synthesis of HALo PROTAC [1] .
- GC81277Boc-C17-COOHCAS: 1643852-37-2Purity: >98.00%
Boc-C17-COOH is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC8127820-Bromoicosanoic acidCAS: 876476-87-8Purity: >98.00%
20-Bromoicosanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81279Tetracosanedioic acidCAS: 2450-31-9Purity: >98.00%
Tetracosanedioic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81280NHBoc-PEG3-ICAS: 1801273-41-5Purity: >97.00%
NHBoc-PEG3-I is a PROTAC linker that can be used in the synthesis of PROTACs.
- GC81281tert-Butyl 17-bromoheptadecanoateCAS: 2428400-70-6Purity: >98.00%
tert-Butyl 17-bromoheptadecanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81258 | tert-Butyl (10-bromodecyl)carbamate | 887353-29-9 | >98.00% | |
tert-Butyl (10-bromodecyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81259 | Tert-butyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridin-1-yl]propanoate | 1802892-92-7 | >98.00% | |
Tert-butyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridin-1-yl]propanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81260 | Cl-C6-PEG3-C3-acid | 1835705-78-6 | >99.50% | |
Cl-C6-PEG3-C3-acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81261 | 1,13-Dibromotridecane | 31772-05-1 | >98.00% | |
1,13-Dibromotridecane is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81262 | Docosane-1,22-diol | 22513-81-1 | >98.00% | |
Docosane-1,22-diol is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81263 | 14-((tert-Butoxycarbonyl)amino)tetradecanoic acid | 2307778-46-5 | >98.00% | |
14-((tert-Butoxycarbonyl)amino)tetradecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81264 | Boc-PEG2-I | 1938057-43-2 | >98.00% | |
Boc-PEG2-I is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81265 | Tert-butyl methyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)carbamate | 936728-17-5 | >98.00% | |
Tert-butyl methyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81266 | tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)carbamate | 360792-43-4 | >98.00% | |
tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81267 | 3-(4-((1-(Tert-butoxycarbonyl)piperidin-4-yl)oxy)phenyl)propanoic acid | 1080421-71-1 | >98.00% | |
3-(4-((1-(Tert-butoxycarbonyl)piperidin-4-yl)oxy)phenyl)propanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81268 | tert-Butyl (11-bromoundecyl)carbamate | 463930-53-2 | >98.00% | |
tert-Butyl (11-bromoundecyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81269 | tert-Butyl (8-iodooctyl)carbamate | 2011713-75-8 | >98.00% | |
tert-Butyl (8-iodooctyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81270 | Boc-C15-COOH | 905302-44-5 | >98.00% | |
Boc-C15-COOH is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81271 | 1,14-Dibromotetradecane | 37688-96-3 | >97.00% | |
1,14-Dibromotetradecane is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81272 | Henicosanedioic acid | 505-55-5 | >98.00% | |
Henicosanedioic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81273 | 1,15-Dibromopentadecane | 81726-81-0 | >98.00% | |
1,15-Dibromopentadecane is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81274 | 16-((tert-Butoxycarbonyl)amino)hexadecanoic acid | 135747-73-8 | >98.00% | |
16-((tert-Butoxycarbonyl)amino)hexadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81275 | Boc-C14-Br | 905302-64-9 | >98.00% | |
Boc-C14-Br is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81276 | N3-PEG5-C6-Cl | 1261238-21-4 | >99.50% | |
N3-PEG5-C6-Cl is a PEG PROTAC linker, can be used for synthesis of HALo PROTAC [1] . | ||||
| GC81277 | Boc-C17-COOH | 1643852-37-2 | >98.00% | |
Boc-C17-COOH is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81278 | 20-Bromoicosanoic acid | 876476-87-8 | >98.00% | |
20-Bromoicosanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81279 | Tetracosanedioic acid | 2450-31-9 | >98.00% | |
Tetracosanedioic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81280 | NHBoc-PEG3-I | 1801273-41-5 | >97.00% | |
NHBoc-PEG3-I is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||
| GC81281 | tert-Butyl 17-bromoheptadecanoate | 2428400-70-6 | >98.00% | |
tert-Butyl 17-bromoheptadecanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||