Deoxytmidine-5'-triphosphate-13C10 (dTTP-13C10) dilithium is 13C-labeled Deoxytmidine-5'-triphosphate . Deoxytmidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxytmidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
Stable heavy isotopes of drogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[2]. Tattersall MH, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975;5(2):191-202.