Glycycoumarin |
| Catalog No.GC36163 |
글리시쿠마린은 강력한 진경제입니다. Glycycoumarin은 감초의 주요 생리 활성 쿠마린이며 진경제 활성을 나타냅니다. Glycycoumarin은 또한 간 보호 효과가 있습니다. 글리시쿠마린은 복통 및 간 질환 연구에 사용할 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 94805-82-0
Sample solution is provided at 25 µL, 10mM.
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Glycycoumarin is a major bioactive coumarin of licorice. Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress-mediated JNK and GSK-3-mediated mitochondrial pathway. Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase [1] [2].
[1]. Zhang E, et al. Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway. Sci Rep. 2016 Nov 30;6:38138. [2]. Song X, et al. Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase. Oncotarget. 2016 Oct 4;7(40):65732-65743.
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