LSD1-IN-6 |
| Catalog No.GC36485 |
LSD1-IN-6(화합물 4m)은 IC50이 123nM인 라이신 특이적 데메틸라제 1(LSD1)의 강력하고 가역적인 억제제입니다. LSD1-IN-6은 히스톤 H3의 디메틸화된 Lys4를 증가시키고 LSD1의 발현에 영향을 미치지 않습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2035912-43-5
Sample solution is provided at 25 µL, 10mM.
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LSD1-IN-6 (Compound 4m) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 123 nM. LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1]. IC50: 123 nM (LSD1)[1]
[1]. Duan YC, et al. Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation. Eur J Med Chem. 2017 Jan 27;126:246-258.
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