PROTAC FAK degrader 1 |
| Catalog No.GC36985 |
PROTAC FAK 분해기 1은 IC50이 6.5nM, DC50이 3nM인 선택적이고 강력한 von Hippel-Lindau 기반 초점 접착 키나제(FAK) 분해기입니다.
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Cas No.: 2301916-69-6
Sample solution is provided at 25 µL, 10mM.
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PROTAC FAK degrader 1 is a selective and potent focal adhesion kinase (Fak) degrader with an IC50 of 6.5 nM, DC50 of 3 nM[1]. IC50: 6.5 nM (Focal adhesion kinase)DC50: 3 nM (Focal adhesion kinase)[1]
[1]. Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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