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Graphislactone A

Catalog No.GC18788

Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M.

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Graphislactone A Chemical Structure

Cas No.: 52179-44-9

Size 가격 재고 수량
1mg
US$438.00
재고 있음
5mg
US$1,531.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislactone A reduces peroxidation of human LDL and slows peroxidation of linoleic acid by 4.4-fold. It also inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM.

References:
[1]. Song, Y.C., Huang, W.Y., Sun, C., et al. Characterization of graphislactone A as the antioxidant and free radical-scavenging substance from the culture of Cephalosporium sp. IFB-E001, an endophytic fungus in Trachelospermum jasminoides Biol. Pharm. Bull. 28(3), 506-509 (2005).
[2]. Hormazabal, E., Schmeda-Hirschmann, G., Astudillo, L., et al. Metabolites from Microsphaeropsis olivacea, an endophytic fungus of Pilgerodendron uviferum Z. Naturforsch. C. 60(1-2), 11-21 (2005).

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