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홈 >> Signaling Pathways >> Neuroscience

Neuroscience

Neuroscience

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides).

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  1. CAS 등록 번호 상품명 정보
  2. GC63267 α-​Chaconine α-Chaconine은 전사 수준에서 COX-2, IL-1β, IL-6 및 TNF-α의 발현을 억제합니다. α-​Chaconine Chemical Structure
  3. GC49097 α-Conotoxin AuIB (trifluoroacetate salt) A conotoxin and an antagonist of α3β4 subunit-containing nAChRs α-Conotoxin AuIB (trifluoroacetate salt) Chemical Structure
  4. GC26093 α-Conotoxin GI α-Conotoxin GI, a 13-residue peptide originally isolated from the venom of the fish-hunting cone snail Conus geographus, acts as a competitive antagonist for the muscle-type nicotinic acetylcholine receptor (nAChR) with excellent selectivity for α/δ receptor subunit binding over α/γ. α-Conotoxin GI Chemical Structure
  5. GC49140 α-Conotoxin ImI (trifluoroacetate salt) A conotoxin and an antagonist of α7 nAChRs α-Conotoxin ImI (trifluoroacetate salt) Chemical Structure
  6. GC49838 α-Cortolone A metabolite of cortisol α-Cortolone Chemical Structure
  7. GC40262 α-Humulene α-Humulene은 Tanacetum vulgare L의 주성분입니다. α-Humulene Chemical Structure
  8. GC64563 α-Methylserotonin α-Methylserotonin Chemical Structure
  9. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) α-MSH(⋱-멜라닌 세포 자극 호르몬) TFA는 내인성 신경 펩티드이며 항염 및 해열 활성을 갖는 내인성 멜라노코르틴 수용체 4(MC4R) 작용제입니다. α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  10. GC41499 α-Phellandrene α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities. α-Phellandrene Chemical Structure
  11. GC10873 α-Spinasterol α-Spinacia oleracea에서 분리된 Spinasterol은 항균 활성이 있습니다. α-Spinasterol Chemical Structure
  12. GC63615 α-Thujone α-Thujone은 강력한 항종양 활성을 가진 Thuja occidentalis 에센셜 오일에서 분리된 모노테르펜입니다. α-Thujone Chemical Structure
  13. GC49467 β-Aescin A triterpenoid saponin with diverse biological activities β-Aescin Chemical Structure
  14. GC63273 β-Amyloid (1-14),mouse,rat β-Amyloid (1-14),mouse,rat Chemical Structure
  15. GC66089 β-Amyloid (1-40) (TFA) β-아밀로이드(1-40) TFA는 알츠하이머병 환자의 뇌에서 발견되는 플라크의 주요 단백질입니다.821d96072c2d58d8970e76f526b0f6b8 β-Amyloid (1-40) (TFA) Chemical Structure
  16. GC63274 β-Amyloid (1-42), (rat/mouse) (TFA) β-Amyloid (1-42), (rat/mouse) (TFA) Chemical Structure
  17. GC37984 β-Amyloid (1-42), rat β-아밀로이드(1-42), 쥐는 42-aa 펩타이드이며 급성 해마 조각에 대한 세포독성 효과를 나타내며 알츠하이머병 연구에 사용됩니다. β-Amyloid (1-42), rat Chemical Structure
  18. GC66416 β-Amyloid (22-35) (TFA) β-아밀로이드 22-35(아밀로이드 β-단백질 22-35) β-아밀로이드 단백질의 잔기 22-35 단편인 TFA는 무혈청 배지에서 래트 해마로부터 배양된 뉴런에 세포독성 효과를 갖는다. 821d96072c2d58d8970e76f526b0f6b8β-아밀로이드 22-35 TFA는 응집체를 형성하고 β-중성 완충액에서 아밀로이드 단백질과 유사한 전형적인 아밀로이드 원섬유를 형성합니다.821d96072c2d58d8970e76f526b0f6b8 β-Amyloid (22-35) (TFA) Chemical Structure
  19. GC66346 β-Amyloid (42-1), human TFA β- 아밀로이드(42-1), 인간 TFA는 아밀로이드의 불활성 형태인 β 821d96072c2d58d8970e76f526b0f6b8펩티드(1-42). 821d96072c2d58d8970e76f526b0f6b8β-아밀로이드(42-1), 인간 TFA는 알츠하이머병의 병인에서 중요한 역할을 하는 42-아미노산 펩티드입니다.821d96072c2d58d8970e76f526b0f6b8 β-Amyloid (42-1), human TFA Chemical Structure
  20. GC37986 β-Amyloid 1-17 β-Amyloid 1-17은 β-Amyloid의 펩타이드로, 섬유를 안정화시키고 Aβ 섬유 형성에 역할을 합니다. β-Amyloid 1-17 Chemical Structure
  21. GC37987 β-Amyloid 1-20 β-아밀로이드 1-20은 베타 아밀로이드 단백질의 아미노산 1에서 20으로 구성됩니다. β-Amyloid 1-20 Chemical Structure
  22. GC37993 β-Amyloid 1-9 β-베타 아밀로이드의 N-말단 단편인 아밀로이드 1-9는 아미노산 잔기 1에서 9로 구성됩니다. β-Amyloid 1-9 Chemical Structure
  23. GC37985 β-Amyloid 11-22 β-아밀로이드 11-22는 β-아밀로이드의 펩타이드 단편입니다. β-Amyloid 11-22 Chemical Structure
  24. GC37988 β-Amyloid 12-20 β-아밀로이드 12-20은 β-아밀로이드의 펩티드 단편입니다. β-Amyloid 12-20 Chemical Structure
  25. GC37991 β-Amyloid 15-21 β-Amyloid 15-21 Chemical Structure
  26. GC37992 β-Amyloid 18-28 β-아밀로이드 18-28은 β-아밀로이드의 펩티드 단편입니다. β-Amyloid 18-28 Chemical Structure
  27. GC37994 β-Amyloid 22-40 β-아밀로이드 22-40은 β-아밀로이드의 펩타이드 단편입니다. β-Amyloid 22-40 Chemical Structure
  28. GC37995 β-Amyloid 33-40 β-아밀로이드 33-40은 베타 아밀로이드 단백질의 아미노산 33~40으로 구성된 펩타이드입니다. β-Amyloid 33-40 Chemical Structure
  29. GC37996 β-Amyloid 35-42 β-아밀로이드 35-42는 베타 아밀로이드 단백질의 아미노산 35~42로 구성된 펩타이드입니다. β-Amyloid 35-42 Chemical Structure
  30. GC37997 β-Amyloid 4-10 β-아밀로이드 4-10은 다클론 항-Aβ(1-42) 항체에 대한 에피토프이며, 형질전환 알츠하이머병 마우스 모델에서 아밀로이드 침착을 감소시킵니다. β-Amyloid 4-10 Chemical Structure
  31. GC34944 β-CGRP, human TFA β-CGRP, human TFA Chemical Structure
  32. GC41623 β-Elemonic Acid β-엘레몬산은 보스웰리아 파피리페라에서 분리된 트리테르펜입니다. β-Elemonic Acid Chemical Structure
  33. GC45234 β-Endorphin (1-27) (human) (trifluoroacetate salt) β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors). β-Endorphin (1-27) (human) (trifluoroacetate salt) Chemical Structure
  34. GC45236 β-Endorphin (rat) β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities. β-Endorphin (rat) Chemical Structure
  35. GC52494 β-Endorphin (rat) (trifluoroacetate salt) An opioid neuropeptide β-Endorphin (rat) (trifluoroacetate salt) Chemical Structure
  36. GC49769 β-Glucogallin A plant metabolite and an aldose reductase 2 inhibitor β-Glucogallin Chemical Structure
  37. GC40105 βARK1 Inhibitor βARK1 억제제(메틸 5-[2-(5-니트로-2-푸릴)비닐]-2-푸로에이트)는 GRK2(β-ARK1) 억제제입니다. βARK1 Inhibitor Chemical Structure
  38. GC38010 γ-Aminobutyric acid γ-Aminobutyric acid Chemical Structure
  39. GC64508 γ-Aminobutyric acid-d6 γ-Aminobutyric acid-d6 Chemical Structure
  40. GC49865 γ-D-Glutamylglycine (trifluoroacetate salt) An excitatory amino acid antagonist γ-D-Glutamylglycine (trifluoroacetate salt) Chemical Structure
  41. GC48313 γ-Lindane An insecticide and GABAA receptor antagonist γ-Lindane Chemical Structure
  42. GC10872 α-Conotoxin AuIB α-Conotoxin AuIB, a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist, blocks α3β4 nAChRs expressed in Xenopus oocytes with an IC50 of 0.75 μM. α-Conotoxin AuIB Chemical Structure
  43. GC13644 α-Conotoxin EI Selective antagonist of neuromuscular nicotinic receptors α1β1γδ α-Conotoxin EI Chemical Structure
  44. GC14353 α-Conotoxin ImI Nicotinic receptor antagonist α-Conotoxin ImI Chemical Structure
  45. GC14296 α-Conotoxin PIA &알파;-코노톡신 PIA는 -6 및 α3 하위 단위를 포함하는 nAChR 하위 유형을 표적으로 하는 니코틴성 아세틸콜린 수용체(nAChR) 길항제입니다. α-Conotoxin PIA Chemical Structure
  46. GC10368 α-Conotoxin PnIA α-코노톡신 PnIA는 포유동물 α7 nAChR의 강력하고 선택적인 길항제로서 신경병증성 통증 및 알츠하이머병과 같은 신경학적 상태의 연구에 대한 잠재력을 가지고 있습니다. α-Conotoxin PnIA Chemical Structure
  47. GC11577 α-Methyl-5-hydroxytryptamine maleate 5-HT2B receptor agonist α-Methyl-5-hydroxytryptamine maleate Chemical Structure
  48. GC34242 β-Amyloid (1-42), rat TFA β-Amyloid (1-42), rat TFA Chemical Structure
  49. GC31146 β-Amyloid (10-35), amide β-아밀로이드(10-35), 아미드는 26개의 aa(Aβ 펩티드의 10-35개 잔기)로 구성되며 알츠하이머병의 아밀로이드 플라크의 주요 구성요소입니다. β-Amyloid (10-35), amide Chemical Structure
  50. GC31129 β-Amyloid 1-16 (Amyloid β-Protein (1-16)) &베타;-아밀로이드 1-16(아밀로이드 &베타;-단백질(1-16))은 β입니다.-아밀로이드 단백질 단편은 금속 결합에 관여합니다. β-Amyloid 1-16 (Amyloid β-Protein (1-16)) Chemical Structure
  51. GC31171 β-Amyloid 1-28 (Amyloid β-Protein (1-28)) &베타;-아밀로이드 1-28(아밀로이드 &베타;-단백질(1-28))은 β입니다.-아밀로이드 단백질 단편은 금속 결합에 관여합니다. β-Amyloid 1-28 (Amyloid β-Protein (1-28)) Chemical Structure
  52. GC30325 β-Amyloid 22-35 (Amyloid β-Protein (22-35)) β-아밀로이드 22-35(아밀로이드 ⋲-단백질 22-35), &7#8946의 잔기 22-35 단편. β-Amyloid 22-35 (Amyloid β-Protein (22-35)) Chemical Structure
  53. GC31137 β-Amyloid 29-40 (Amyloid beta-protein(29-40)) &베타;-아밀로이드 29-40(아밀로이드 베타-단백질(29-40))은 아밀로이드-β의 단편입니다. 펩타이드. β-Amyloid 29-40 (Amyloid beta-protein(29-40)) Chemical Structure
  54. GC31179 β-Amyloid 31-35 &베타;-아밀로이드 31-35는 신경독성 활성을 유지하는 천연 아밀로이드-β 펩티드의 가장 짧은 서열입니다. β-Amyloid 31-35 Chemical Structure
  55. GC11449 β-CCB

    benzodiazepine receptor ligand

     β-CCB Chemical Structure
  56. GC33595 β-CGRP, human (Human β-CGRP) &베타;-CGRP, 인간(인간 &베타;-CGRP)(인간 β-CGRP)은 칼시토닌 펩티드 중 하나이며, 칼시토닌 수용체 유사 수용체(CRLR) 및 수용체 활성) 변형 단백질(RAMP)의 복합체를 통해 작용합니다. , 셀의 CRLR/RAMP1 및 CRLR/RAMP2에 대해 1nM 및 300nM의 IC50이 있습니다. β-CGRP, human (Human β-CGRP) Chemical Structure
  57. GC18033 γDGG γDGG는 경쟁력 있는 AMPA 수용체 차단제입니다. γDGG Chemical Structure
  58. GC52013 (±)-10-hydroxy-12(Z)-Octadecenoic Acid An oxylipin and metabolite of linoleic acid (±)-10-hydroxy-12(Z)-Octadecenoic Acid Chemical Structure
  59. GC52421 (±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5 An internal standard for the quantification of (±)-10-hydroxy-12(Z)-octadecenoic acid (±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5 Chemical Structure
  60. GC41657 (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide) (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively). (±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide) Chemical Structure
  61. GC41658 (±)-2-hydroxy Ibuprofen (±)-2-하이드록시 이부프로펜은 이부프로펜의 대사 산물입니다. (±)-2-hydroxy Ibuprofen Chemical Structure
  62. GC62726 (±)-Amiflamine (±)-아미플라민(FLA 336)은 pIC50이 5.57인 강력한 모노아민 산화효소-A(MAO-A) 억제제입니다. (±)-Amiflamine Chemical Structure
  63. GC12774 (±)-Anatoxin A fumarate (±)-Anatoxin A fumarate는 담수 시아노박테리움에서 분리된 천연 알칼로이드입니다. (±)-Anatoxin A fumarate Chemical Structure
  64. GC46272 (±)-Asenapine-13C-d3 (hydrochloride) An internal standard for the quantification of (±)-asenapine (±)-Asenapine-13C-d3 (hydrochloride) Chemical Structure
  65. GC46274 (±)-Baclofen-d4 (±)-Baclofen-d4는 Baclofen으로 표시된 중수소입니다. (±)-Baclofen-d4 Chemical Structure
  66. GC60394 (±)-Duloxetine hydrochloride (±)-둘록세틴((Rac)-둘록세틴) 염산염은 둘록세틴 염산염의 라세미체입니다. (±)-Duloxetine hydrochloride Chemical Structure
  67. GC14410 (±)-Epibatidine nicotinic agonist (±)-Epibatidine Chemical Structure
  68. GC46288 (±)-Epibatidine (hydrochloride) An agonist of α4β2 subunit-containing nAChRs (±)-Epibatidine (hydrochloride) Chemical Structure
  69. GC46290 (±)-Ibuprofen-d3 이부프로펜 D3는 이부프로펜이라고 표시된 중수소입니다. (±)-Ibuprofen-d3 Chemical Structure
  70. GC49515 (±)-Ibuprofen-d3 (sodium salt) An internal standard for the quantification of (±)-ibuprofen (±)-Ibuprofen-d3 (sodium salt) Chemical Structure
  71. GC45278 (±)-Ketoprofen-d3   (±)-Ketoprofen-d3 Chemical Structure
  72. GC12699 (±)-LY 395756 ligand for mGlu2 and mGlu3 receptor (±)-LY 395756 Chemical Structure
  73. GC16735 (±)-McN 5652 5-HT uptake inhibitor (±)-McN 5652 Chemical Structure
  74. GC46302 (±)-Muscarine (hydrate) An agonist of muscarinic acetylcholine receptors (±)-Muscarine (hydrate) Chemical Structure
  75. GC49875 (±)-N-desmethyl Venlafaxine (hydrochloride) A minor active metabolite of venlafaxine (±)-N-desmethyl Venlafaxine (hydrochloride) Chemical Structure
  76. GC46305 (±)-Nicotine-d3 An internal standard for the quantification of (±)-nicotine (±)-Nicotine-d3 Chemical Structure
  77. GC14834 (±)-Nipecotic acid GABA uptake inhibitor (±)-Nipecotic acid Chemical Structure
  78. GC41676 (±)-Nornicotine (±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. (±)-Nornicotine Chemical Structure
  79. GC49482 (±)-Nornicotine-d4 An internal standard for the quantification of (±)-nornicotine (±)-Nornicotine-d4 Chemical Structure
  80. GC12394 (±)-trans-ACPD (±)-trans-ACPD, 대사성 수용체 작용제는 배양된 소뇌 Purkinje 뉴런에서 칼슘 동원 및 내부 전류를 생성합니다. (±)-trans-ACPD Chemical Structure
  81. GC11128 (±)-Vesamicol hydrochloride (±)-Vesamicol 염산염((±)-AH5183 염산염)은 Ki가 2nM인 강력한 소포성 아세틸콜린 수송 억제제입니다. (±)-Vesamicol hydrochloride Chemical Structure
  82. GC41685 (±)-WIN 55,212 (mesylate) (±)-WIN 55,212-2 is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki value of 62.3 and 3.3 nM for human recombinant central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively. (±)-WIN 55,212 (mesylate) Chemical Structure
  83. GC41213 (±)10-HDHA

    (±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

     (±)10-HDHA Chemical Structure
  84. GC41214 (±)11-HDHA (±)11-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)11-HDHA Chemical Structure
  85. GC40467 (±)11-HETE (±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. (±)11-HETE Chemical Structure
  86. GC40802 (±)12(13)-DiHOME

    (±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.

     (±)12(13)-DiHOME Chemical Structure
  87. GC41191 (±)13(14)-EpDPA (±)13(14)-EpDPA(13,14-EpDPE)는 시토크롬 P-450 에폭시게나제와 도코사헥사엔산(DHA)의 반응 생성물입니다. (±)13(14)-EpDPA Chemical Structure
  88. GC41192 (±)13-HDHA (±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)13-HDHA Chemical Structure
  89. GC41193 (±)14-HDHA (±)14-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)14-HDHA Chemical Structure
  90. GC41194 (±)16(17)-EpDPA

    EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.

     (±)16(17)-EpDPA Chemical Structure
  91. GC41196 (±)16-HDHA (±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)16-HDHA Chemical Structure
  92. GC41197 (±)17-HDHA (±)17-HDHA is an autoxidation product of docosahexaenoic acid in vitro. (±)17-HDHA Chemical Structure
  93. GC41199 (±)19(20)-EpDPA EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. (±)19(20)-EpDPA Chemical Structure
  94. GC41202 (±)4-HDHA (±)4-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)4-HDHA Chemical Structure
  95. GC41203 (±)7(8)-EpDPA Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA Chemical Structure
  96. GC41204 (±)7-HDHA

    (±)7-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

     (±)7-HDHA Chemical Structure
  97. GC41205 (±)8-HDHA (±)8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. (±)8-HDHA Chemical Structure
  98. GC33544 (±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6) (±)-레보메프로마진 D6((±)-메토트리메프라진 D6)은 D3 도파민 및 히스타민 H1 수용체 길항제인 메토트리메프라진으로 표지된 중수소입니다. (±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6) Chemical Structure
  99. GC31026 (±)-Tazifylline (±)-Tazifylline은 강력하고 선택적이고 오래 지속되는 히스타민 H1 수용체 길항제입니다. (±)-Tazifylline Chemical Structure
  100. GN10155 (+)- Corydaline (+)- Corydaline Chemical Structure
  101. GC13156 (+)-AJ 76 hydrochloride Dopamine receptor antagonist (+)-AJ 76 hydrochloride Chemical Structure

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