GLPBio

Haspin

Haspin is a serine/threonine-protein kinase that phosphorylates H3T3ph (histone H3 at 'Ser-3') during mitosis. It is essential for the proper cohesion, mataphase aligment and normal cell cycle progression at mitotic centromeres.

Products Related to Haspin(6)

  • GC83626 structure
    GC83626MU1920
    CAS: 3067968-52-6
    Purity: >98.00%

    MU1920 is an ATP-competitive, selective inhibitor for haspin with an IC 50 of 6 nM.

  • GC17254 structure
    GC17254CHR-6494
    CAS: 1333377-65-3
    Purity: >98.50%

    A selective Haspin protein kinase inhibitor

  • GC33086 structure
    GC33086LDN-192960
    CAS: 184582-62-5
    Purity: >99.50%

    LDN-192960은 IC50이 각각 10nM 및 48nM인 Haspin 및 Dual-specificity Tyrosine-regulated Kinase 2(DYRK2)의 억제제입니다.

  • GC44047 structure
    GC44047LDN-192960 (hydrochloride)
    CAS: 2309172-48-1
    Purity: >98.00%

    LDN-192960 is an inhibitor of haspin protein kinase and dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) with IC50 values of 10 and 48 nM, respectively.

  • GC50145 structure
    GC50145CHR 6494 trifluoroacetate
    CAS: 1458630-17-5
    Purity: >98.00%

    CHR 6494 트리플루오로아세테이트는 IC50이 2nM인 강력한 하스핀 억제제입니다. CHR 6494 트리플루오로아세테이트는 히스톤 H3T3 인산화를 억제합니다. CHR 6494 트리플루오로아세테이트는 흑색종 및 유방암을 포함한 암세포의 세포자멸사를 유도합니다. CHR 6494 트리플루오로아세테이트는 암 연구에 사용할 수 있습니다.

  • GC69207 structure
    GC69207Haspin-IN-3
    CAS: 2416569-95-2
    Purity: >98.00%

    Haspin-IN-3 (화합물 8l)은 효과적인 haspin 억제제로, IC50 값은 14 nM입니다. Haspin-IN-3은 항암 작용을 가지고 있습니다.