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홈 >> Signaling Pathways >> Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.

Targets for  Cell Cycle/Checkpoint

Products for  Cell Cycle/Checkpoint

  1. Cat.No. 상품명 정보
  2. GC40702 α-D-Galactopyranosylphenyl isothiocyanate

    α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.

     α-D-Galactopyranosylphenyl isothiocyanate Chemical Structure
  3. GC41676 (±)-Nornicotine (±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. (±)-Nornicotine Chemical Structure
  4. GC49482 (±)-Nornicotine-d4 An internal standard for the quantification of (±)-nornicotine (±)-Nornicotine-d4 Chemical Structure
  5. GC41684 (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups. (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane Chemical Structure
  6. GC40802 (±)12(13)-DiHOME

    (±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.

     (±)12(13)-DiHOME Chemical Structure
  7. GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol 2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol Chemical Structure
  8. GC45890 (+)-Abscisic Acid-d6 (+)-Abscisic Acid-d6(ABA-d6)은 Abscisic acid로 표지된 중수소입니다. (+)-Abscisic Acid-d6 Chemical Structure
  9. GC62728 (1E)-CFI-400437 dihydrochloride (1E)-CFI-400437 이염산염은 강력한 PLK4(IC50=0.6nM) 억제제이며 PLK 계열의 다른 구성원(>10μM)에 대해 선택적입니다. (1E)-CFI-400437 이염산염은 각각 0.37, 0.21, 0.48 및 0.18μM의 IC50으로 Aurora A, Aurora B, KDR 및 FLT-3을 억제합니다. 항증식 활동. (1E)-CFI-400437 dihydrochloride Chemical Structure
  10. GC49690 (3R,5R)-Rosuvastatin (calcium salt) A potential impurity found in bulk preparations of rosuvastatin (3R,5R)-Rosuvastatin (calcium salt) Chemical Structure
  11. GC41268 (E)-2-Hexadecenal Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase. (E)-2-Hexadecenal Chemical Structure
  12. GC41701 (E)-2-Hexadecenal Alkyne (E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal that can be used as a click chemistry probe. (E)-2-Hexadecenal Alkyne Chemical Structure
  13. GC46335 (E)-Fenpyroximate (E)-Fenpyroximate는 강력한 살비제입니다. (E)-Fenpyroximate Chemical Structure
  14. GC10419 (R)-CCG-1423 Rho inhibitor (R)-CCG-1423 Chemical Structure
  15. GC16429 (R)-DRF053 dihydrochloride cdk/CK1 inhibitor,potent and ATP-competitive (R)-DRF053 dihydrochloride Chemical Structure
  16. GC41719 (R)-nitro-Blebbistatin (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin. (R)-nitro-Blebbistatin Chemical Structure
  17. GC46347 (S)-(+)-Methoprene (S)-메토프렌은 유충 호르몬 유사체로 곤충이 번데기에서 성충으로 변하는 것을 막고 살충제로 사용됩니다. (S)-(+)-Methoprene Chemical Structure
  18. GC41557 (S)-3'-amino Blebbistatin (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-amino Blebbistatin Chemical Structure
  19. GC41484 (S)-3'-hydroxy Blebbistatin (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-hydroxy Blebbistatin Chemical Structure
  20. GC52192 (S)-4'-nitro-Blebbistatin (S)-4'-nitro-Blebbistatin은 생리학적, 발달 및 세포 생물학 연구에서 미오신 II의 특정 역할에 대한 연구에 사용되는 비세포독성, 광안정성, 형광성 및 특정 미오신 II 억제제입니다. (S)-4'-nitro-Blebbistatin Chemical Structure
  21. GC14497 (S)-CCG-1423 Rho inhibitor (S)-CCG-1423 Chemical Structure
  22. GC34999 (S)-Ceralasertib (S)-Ceralasertib((S)-AZD6738)은 특허 WO2011154737A1, 화합물 II에서 추출되며 2.578 nM의 IC50을 나타냅니다.(S)-Ceralasertib은 우수한 전임상 및 PK를 가진 강력하고 선택적인 설폭시민 모르폴리노피리미딘 ATR 억제제입니다. ) 특성.(S)-Ceralasertib은 수용성을 개선하고 CYP3A4 시간 의존적 억제를 제거하기 위해 개발되었습니다. (S)-Ceralasertib Chemical Structure
  23. GC46351 (S)-CR8 (S)-CR8은 CR8의 S-이성질체이다. (S)-CR8은 CDK2/사이클린 E, CDK2/사이클린 A, CDK9/사이클린 T, CDK5/p25 및 CDK1/사이클린에 대해 IC50이 0.060, 0.080, 0.11, 0.12 및 0.15μM인 강력하고 선택적인 CDK 억제제입니다. B, 각각. (S)-CR8은 SH-SY5Y 세포 생존을 감소시킵니다(IC50 0.40μM). (S)-CR8 Chemical Structure
  24. GC41737 (S)-Glycyl-H-1152 (hydrochloride) Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. (S)-Glycyl-H-1152 (hydrochloride) Chemical Structure
  25. GC40145 (S)-Laudanosine (S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium. (S)-Laudanosine Chemical Structure
  26. GC41739 (S)-nitro-Blebbistatin (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-nitro-Blebbistatin Chemical Structure
  27. GC18275 1,2-Dihexadecyl-sn-glycero-3-PC 1,2-Dihexadecyl-sn-glycero-3-PC is a synthetic ether-linked phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions. 1,2-Dihexadecyl-sn-glycero-3-PC Chemical Structure
  28. GC45783 1,2-Dioleoyl-rac-glycerol-13C3 An internal standard for the quantification of 1,2-dioleoyl-rac-glycerol 1,2-Dioleoyl-rac-glycerol-13C3 Chemical Structure
  29. GC46379 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt) 1,2-Dioleoyl-sn-glycero-3-PS(나트륨염)는 포스포세린/포스파티딜세린을 대체합니다. 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt) Chemical Structure
  30. GC41823 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)

    1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid.

     1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt) Chemical Structure
  31. GC46385 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose A ManNAc analog and building block 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose Chemical Structure
  32. GC19528 1,4-Benzoquinone A toxic metabolite of benzene 1,4-Benzoquinone Chemical Structure
  33. GC18726 1-Methyl-1,4-dihydronicotinamide 1-메틸-1,4-디히드로니코틴아미드는 니코틴아미드의 유도체입니다. 1-Methyl-1,4-dihydronicotinamide Chemical Structure
  34. GC49736 10-acetyl Docetaxel 10-아세틸 도세탁셀(10-Acetyl docetaxel)은 항암 활성이 있는 도세탁셀의 유사체입니다. 도세탁셀은 유사분열 억제 활성이 있는 미세소관 분해 억제제입니다. 10-acetyl Docetaxel Chemical Structure
  35. GC12954 10-DAB (10-Deacetylbaccatin) An inhibitor of microtubule assembly 10-DAB (10-Deacetylbaccatin) Chemical Structure
  36. GC35044 10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyl paclitaxel은 개선된 약리학적 특징을 가진 Paclitaxel(미세관 안정화제, tubulin 중합 강화) 유도체입니다. 10-Deacetyl-7-xylosyl paclitaxel Chemical Structure
  37. GC35045 10-Oxo Docetaxel 10-Oxo Docetaxel(Docetaxel Impurity 1)은 놀라운 항종양 특성과 Docetaxel 중간체를 갖는 새로운 분류군입니다. 10-Oxo Docetaxel Chemical Structure
  38. GC17295 10058-F4 10058-F4는 c-Myc 표적 유전자 발현의 c-Myc-Max 이량체화 및 전이활성화를 방지하는 c-Myc 억제제입니다. 10058-F4 Chemical Structure
  39. GC63576 10074-A4 10074-A4는 c-Myc 억제제입니다. 10074-A4는 펩타이드 사슬을 따라 다른 위치에서 c-Myc370-409에 결합할 수 있습니다. 10074-A4는 항암 효과가 있습니다. 10074-A4 Chemical Structure
  40. GC14918 10074-G5 10074-G5는 IC50이 146μM인 c-Myc-Max 이량체화 억제제입니다. 10074-G5 Chemical Structure
  41. GC40448 12(S)-HETE

    12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.

     12(S)-HETE Chemical Structure
  42. GC46434 13C15-Nivalenol An internal standard for the quantification of nivalenol 13C15-Nivalenol Chemical Structure
  43. GC49390 13C6-4-Nitroaniline An internal standard for the quantification of 4-nitroaniline 13C6-4-Nitroaniline Chemical Structure
  44. GC41110 16-epi Latrunculin B 16-epi Latrunculin B, first isolated from the Red Sea sponge N. 16-epi Latrunculin B Chemical Structure
  45. GC48423 19-O-Acetylchaetoglobosin A 19-O-Acetylchaetoglobosin A는 cytochalasan alkaloid로 C. globosum에서 원래 분리된 곰팡이 대사산물로 액틴 중합 억제 및 세포 독성 활성을 가지고 있습니다. 19-O-아세틸키토글로보신 A는 HeLa 자궁경부암 세포에 세포독성을 나타냅니다. 19-O-Acetylchaetoglobosin A Chemical Structure
  46. GC42151 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) 2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) Chemical Structure
  47. GC40947 2,3-Dimethoxy-5-methyl-p-benzoquinone 2,3-Dimethoxy-5-methyl-p-benzoquinone(CoQO)은 강력한 경구 활성 유비퀴논 화합물로 Antrodia cinnamomea에서 추출할 수 있습니다. 2,3-Dimethoxy-5-methyl-p-benzoquinone Chemical Structure
  48. GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene Chemical Structure
  49. GC45324 2,5-dimethyl Celecoxib   2,5-dimethyl Celecoxib Chemical Structure
  50. GC49362 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline A food-derived carcinogen 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline Chemical Structure
  51. GC52029 2-Aminoflubendazole 2-아미노플루벤다졸은 벤지미다졸의 대사산물입니다. 2-Aminoflubendazole Chemical Structure
  52. GC40675 2-deoxy-Artemisinin 2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin. 2-deoxy-Artemisinin Chemical Structure
  53. GC15084 2-Methoxyestradiol (2-MeOE2) 2-Methoxyestradiol (2-MeOE2/2-Me) is a HIF-1α inhibitor that inhibits HIF-1α accumulation and HIF transcriptional activity. 2-Methoxyestradiol can trigger p53-induced apoptosis and has potential antitumor activity.. 2-Methoxyestradiol (2-MeOE2) Chemical Structure
  54. GC52140 2-Methoxyhydroquinone 2-Methoxyhydroquinone Chemical Structure
  55. GC42161 2H-Cho-Arg (trifluoroacetate salt) 2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. 2H-Cho-Arg (trifluoroacetate salt) Chemical Structure
  56. GC40618 3',4',7-Trihydroxyisoflavone 3',4',7-Trihydroxyisoflavone, Daidzein의 주요 대사 산물은 Cot(Tpl2/MAP3K8) 및 MKK4의 ATP 경쟁적 억제제입니다. 3',4',7-트리하이드록시이소플라본은 항암, 항혈관신생, 화학보호 및 자유 라디칼 소거 활성이 있습니다. 3',4',7-Trihydroxyisoflavone Chemical Structure
  57. GC45332 3'-Dephosphocoenzyme A An intermediate in the biosynthesis of CoA 3'-Dephosphocoenzyme A Chemical Structure
  58. GC42239 3,6-diacetoxy Phthalonitrile 3,6-디아세톡시 프탈로니트릴은 세포 투과성 형광 프로브입니다. 3,6-diacetoxy Phthalonitrile Chemical Structure
  59. GC12314 3-(4-Pyridyl)indole 3-(4-피리딜)인돌(Rockout)은 25μM의 IC50을 갖는 Rho-kinase(ROCK) 억제제입니다. 3-(4-Pyridyl)indole Chemical Structure
  60. GC46582 3-Acetyldeoxy Nivalenol-13C17 An internal standard for the quantification of 3-acetyldeoxy nivalenol 3-Acetyldeoxy Nivalenol-13C17 Chemical Structure
  61. GC52129 3-Amino-5-hydroxybenzoic Acid 3-Amino-5-hydroxybenzoic Acid Chemical Structure
  62. GC15389 360A 360A Chemical Structure
  63. GC10115 360A iodide 360A iodide Chemical Structure
  64. GC14186 3MB-PP1 부피가 큰 퓨린 유사체인 3MB-PP1은 Polo-like kinase 1(Plk1) 억제제입니다. 3MB-PP1 Chemical Structure
  65. GC45354 4β-Hydroxywithanolide E 4β, Physalis peruviana L.에서 분리된 하이드록시위타놀라이드 E. 4β-Hydroxywithanolide E Chemical Structure
  66. GC17271 4'-Demethylepipodophyllotoxin An inhibitor of tubulin polymerization 4'-Demethylepipodophyllotoxin Chemical Structure
  67. GC46606 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline A heterocyclic building block 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline Chemical Structure
  68. GC46635 4-deoxy Nivalenol-13C15 An internal standard for the quantification of 4-deoxy nivalenol 4-deoxy Nivalenol-13C15 Chemical Structure
  69. GC18359 4-Epianhydrochlortetracycline (hydrochloride) 4-Epianhydrochlortetracycline is a derivative of tetracycline . 4-Epianhydrochlortetracycline (hydrochloride) Chemical Structure
  70. GC42449 4-Methylumbelliferyl-α-L-Iduronide (free acid) 4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. 4-Methylumbelliferyl-α-L-Iduronide (free acid) Chemical Structure
  71. GC49244 4-oxo Isotretinoin An active metabolite of isotretinoin 4-oxo Isotretinoin Chemical Structure
  72. GC52365 4-tert-Octylphenol monoethoxylate An alkylphenolethoxylate and a degradation product of non-ionic surfactants 4-tert-Octylphenol monoethoxylate Chemical Structure
  73. GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone An active metabolite of various polyphenols 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone Chemical Structure
  74. GC46681 5-Bromouridine A brominated uridine analog 5-Bromouridine Chemical Structure
  75. GC45357 5-Chlorouracil   5-Chlorouracil Chemical Structure
  76. GC41156 5-Octyl D-glutamate 5-Octyl D-glutamate, also known as 5-octyl ester D-glutamate, is a stable, cell-permeable molecule that generates free D-glutamate upon hydrolysis of the ester bond by cytoplasmic esterases. 5-Octyl D-glutamate Chemical Structure
  77. GC41423 5-trans Prostaglandin E2 5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1. 5-trans Prostaglandin E2 Chemical Structure
  78. GC42586 6α-hydroxy Paclitaxel 6α-하이드록시 파클리탁셀은 파클리탁셀의 1차 대사산물입니다. 6α-하이드록시 파클리탁셀은 파클리탁셀과 유사한 억제 효능으로 유기 음이온 수송 폴리펩타이드 1B1/SLCO1B1(OATP1B1)에 대한 시간 의존적 효과를 유지하지만, 더 이상 OATP1B3의 시간 의존적 억제를 나타내지 않습니다. 6α-hydroxy Paclitaxel은 암 연구에 사용할 수 있습니다. 6α-hydroxy Paclitaxel Chemical Structure
  79. GC45969 6β-hydroxy Eplerenone A major metabolite of eplerenone 6β-hydroxy Eplerenone Chemical Structure
  80. GC46721 6-Chloro-2-fluoropurine A heterocyclic building block 6-Chloro-2-fluoropurine Chemical Structure
  81. GC48721 6-O-Demethyl Griseofulvin A metabolite of griseofulvin 6-O-Demethyl Griseofulvin Chemical Structure
  82. GC15478 6H05 6H05는 발암성 돌연변이 K-Ras(G12C)의 선택적 알로스테릭 억제제입니다. 6H05 Chemical Structure
  83. GC40202 7α-hydroxy Cholesterol-d7

    7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.

     7α-hydroxy Cholesterol-d7 Chemical Structure
  84. GC46733 7,12-Dimethylbenz[a]anthracene 7,12-Dimethylbenz[a]anthracene은 다환 방향족 탄화수소(PAH)로서 발암 활성이 있습니다. 7,12-디메틸벤즈[a]안트라센은 다양한 설치류 모델에서 종양 형성을 유도하는 데 사용됩니다. 7,12-Dimethylbenz[a]anthracene Chemical Structure
  85. GC35188 7-Epi-10-oxo-docetaxel 7-Epi-10-oxo-docetaxel(Docetaxel Impurity 2)은 고성능 액체 크로마토그래피(HPLC)에 의해 검출된 도세탁셀의 불순물이다. 7-Epi-10-oxo-docetaxel Chemical Structure
  86. GC35189 7-Epi-docetaxel 7-에피-10-옥소-도세탁셀(도세탁셀 불순물 C; 7-에피탁소테레)은 도세탁셀의 불순물이다. 7-Epi-docetaxel Chemical Structure
  87. GN10625 7-Epitaxol 7-Epitaxol Chemical Structure
  88. GC42610 7-hydroxy Pestalotin 7-하이드록시 페스탈로틴(LL-P880β)은 곰팡이 대사산물입니다. 7-hydroxy Pestalotin Chemical Structure
  89. GC42616 7-oxo Staurosporine

    7-oxo Staurosporine is an antibiotic originally isolated from S.

     7-oxo Staurosporine Chemical Structure
  90. GC35197 7-xylosyltaxol 7-xylosyltaxol(Taxol-7-xyloside)은 탁솔(Paclitaxel) 유도체이고; Paclitaxel은 tubulin에 결합하고 microtubules의 분해를 억제합니다. 7-xylosyltaxol Chemical Structure
  91. GC52126 8-chloro Caffeine 8-chloro Caffeine Chemical Structure
  92. GC40844 9-(2,2-Dicyanovinyl)julolidine 9-(2,2-Dicyanovinyl)julolidine(9-(2,2-Dicyanovinyl)julolidine)은 분자 회전자이자 독특한 형광 염료로 tubulin과 actin에 결합하여 중합 시 형광 강도를 급격히 증가시킵니다. 9-(2,2-Dicyanovinyl)julolidine Chemical Structure
  93. GC48986 9-hydroxy Stearic Acid A hydroxy fatty acid 9-hydroxy Stearic Acid Chemical Structure
  94. GC42665 AAF-CMK (trifluoroacetate salt) Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK (trifluoroacetate salt) Chemical Structure
  95. GC35216 AAPK-25 AAPK-25는 항종양 활성이 있는 강력하고 선택적인 Aurora/PLK 이중 억제제로, 생체지표 히스톤 H3Ser10 인산화에 따라 세포자멸사 급증이 뒤따르는 전중기 단계에서 유사분열 지연 및 세포 정지를 유발할 수 있습니다. AAPK-25는 Kd 값이 23-289nM인 Aurora-A, -B 및 -C와 Kd 값이 55-456nM인 PLK-1, -2 및 -3을 대상으로 합니다. AAPK-25 Chemical Structure
  96. GC25025 Abraxane Abraxane (Nab-Paclitaxel), a novel solvent-free taxane with the binding ratio of Paclitaxel to human serum albumin of 1:9, is an anti-microtubule drug that promotes microtubule aggregation in tubulin dimer and inhibits microtubule depolymerization to stabilize the microtubule system. Abraxane Chemical Structure
  97. GC15875 ABT-751 (E7010) ABT-751(E7010)(E 7010)은 신경모세포종 및 비신경모세포종 세포주에서 IC50이 각각 약 1.5 및 3.4 μM인 새로운 생체이용 가능한 튜불린 결합 및 유사분열 방지 설폰아미드 제제입니다. ABT-751 (E7010) Chemical Structure
  98. GC42683 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1). Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp Chemical Structure
  99. GC52499 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt) A sensitive substrate for neutrophil elastase Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt) Chemical Structure
  100. GC42684 Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1). Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) Chemical Structure
  101. GA20494 Ac-Asp-Glu-Val-Asp-pNA The cleavage of the chromogenic caspase-3 substrate Ac-DEVD-pNA can be monitored at 405 nm. Ac-Asp-Glu-Val-Asp-pNA Chemical Structure

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