Nucleic Acid Turnover/Signaling

Akt1, 2, and 3 are serine/threonine protein kinases in the phosphatidylinositol 3 (PI3)-kinase signalling pathway that play a critical role in the regulation of cell proliferation and survival.

8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents.

MST-312는 강력한 텔로머라제 억제제로 IC50 값은 0.67μM이다.

β-Amanitin은 유독한 Amanita phalloides 버섯에 있는 고리형 펩티드 독소입니다. β-Amanitin은 진핵생물 RNA 중합효소 II 및 III를 억제합니다. β-아마니틴은 단백질 합성을 억제합니다. β-아마니틴은 항체-약물 접합체(ADC)의 세포독성 성분으로 사용될 수 있습니다.

Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S.

Ciprofloxacin-d8 is intended for use as an internal standard for the quantification of ciprofloxacin by GC- or LC-MS.

Tigecycline-d9 is intended for use as an internal standard for the quantification of tigecycline by GC- or LC-MS.

Dihydroresveratrol is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota.

6-아미노페난트리딘은 리보솜(PFAR)의 단백질 접힘 활성을 억제합니다.

(R)-Gyramide A(염산염)는 3.3μM의 IC50 값으로 슈퍼코일링 활성을 방해하는 박테리아 DNA 자이라제 억제제입니다.

5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS.

Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (H2O2), as it oxidizes specific substrates in the presence of water and oxygen.

9-Deazaguanine는 경구 투여 활성을 가진 퓨린 뉴클레오사이드 유사체로 퓨린 뉴클레오사이드 포스포릴라아제 (PNP)의 강력한 억제제로 기능한다.

Ametantrone(NSC 196473)은 DNA에 삽입되어 토포이소머라제 II(TOP2) 매개 DNA 절단을 유도하는 항종양제입니다.

Pemetrexed(나트륨 염 수화물)는 새로운 항엽산제이며, LY231514의 펜타글루타메이트의 Ki 값은 각각 1.3, 7.2 및 65nM입니다. .

Trimethoprim is an antibiotic that inhibits dihydrofolate reductase (DHFR) and shows selectivity for bacterial DHFR over mammalian DHFR (IC50s = 5 and 30,000 nM, respectively).

An internal standard for quantifying doxycycline

An internal standard for the quantification of docosanoic acid

A neuropeptide with diverse biological activities

A neuropeptide with diverse biological activities

A protein synthesis inhibitor with diverse biological activities

A cGAS inhibitor

A cGAS inhibitor

A neuropeptide with diverse biological activities