Tigecycline-d9 (Synonyms: GAR-936-d9) |
| Catalog No.GC40240 |
Tigecycline-d9 is intended for use as an internal standard for the quantification of tigecycline by GC- or LC-MS.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2699607-86-6
Sample solution is provided at 25 µL, 10mM.
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Tigecycline-d9 is intended for use as an internal standard for the quantification of tigecycline by GC- or LC-MS. Tigecycline is a broad-spectrum glycylcycline antibiotic that binds to the bacterial 30S ribosome, blocking the entry of transfer RNA, which halts protein synthesis and inhibits bacterial growth. It is active against a panel of 1,924 European clinical bacterial isolates including S. aureus, S. epidermidis, S. pneumoniae, E. faecalis, E. faecium, E. coli, K. pneumoniae, P. aeruginosa, and P. mirabilis strains (MICs = In vivo, tigecycline (6.25 mg/kg twice daily for 5 days) decreases levels of C. difficile cytotoxin activity and spore formation in cecum and colon in a mouse model of C. difficile infection. Formulations containing tigecycline have been used in the treatment of a variety of bacterial infections.
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