GLPBio

PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt)

Catalog No.: GC92090Purity:>99.00%Synonyms: DPPI-4,5-P2-d62; Phosphatidylinositol-4,5-diphosphate C16-d62; PI(4,5)P2 (16:0/16:0)-d62; PIP2[4',5'](16:0/16:0)-d62
COASDSData Sheet
PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt) 는 GC 또는 LC 질량 스펙트럼을 통해 PtdIns-4,5-P2 1,2- 디팜산나트륨 소금을 정량하는 내표로 사용하도록 설계되었습니다.

제품은 연구용으로만 사용됩니다. 인체에 사용할 수 없으며 환자에게 판매하지 않습니다.

PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt)
25 µgIn Stock
$130.00
1
50 µgIn Stock
$246.00
1
100 µgIn Stock
$462.00
1
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제품 설명 (Description)

PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt) is intended for use as an internal standard for the quantification of PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt) by GC- or LC-mass spectrometry. The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns-4,5-P2-(1,2-dipalmitoyl)-d62 is a synthetic analog of natural PtdIns containing deuterated C16:0 fatty acids at the sn-1 and sn-2 positions. This synthetic standard features the same inositol and diacyl glycerol (DAG) stereochemistry as that of the natural compound. The natural compound is the product of phosphatidylinositol 4-phosphate 5-kinase acting on PtdIns-(4)-P1. Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.

References:
[1]. Exton, J.H.Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteinsAnnu. Rev. Pharmacol. Toxicol.36481-509(1996).
[2]. Majerus, P.W.Inositol phosphate biochemistryAnnu. Rev. Biochem.61225-250(1992).

제품 문서 (Product Documents)

Purity:>99.00%Appearance:A solid
COASDSData Sheet

화학적 특성 (Chemical Properties)

동의어
DPPI-4,5-P2-d62; Phosphatidylinositol-4,5-diphosphate C16-d62; PI(4,5)P2 (16:0/16:0)-d62; PIP2[4',5'](16:0/16:0)-d62
화학명
1-(1,2-dihexadecanoyl(2,2’,3,3’,4,4’,5,5’,6,6’,7,7’,8,8’,9,9’,10,10’,11,11’,12,12’,13,13’,14,14’,15,16,16,16-d31)phosphatidyl)inositol-4,5-bisphosphate, trisodium salt
SMILES
O[C@@H]1[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@@H](O)[C@H]1OP([O-])(OCC(COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)=O.[Na+].[Na+].[Na+]
분자식
C41H16D62O19P3 ? 3Na
분자량
1099.3
보관
-20°C
일반 주의사항
제품의 용해도 데이터에 따라 적절한 용매를 선택하십시오. 조제 후에는 반복적인 동결·해동을 피할 수 있도록 저장 용액을 소분하십시오.
저장 용액은 -80°C 보관 시 6개월 이내, -20°C 보관 시 1개월 이내에 사용하십시오.
용해도를 높이려면 튜브를 37°C로 데운 뒤 적절한 시간 동안 초음파 처리하십시오.
배송 조건
평가용 샘플은 아이스팩과 함께 배송됩니다. 그 외 용량은 실온 배송되며, 요청 시 아이스팩과 함께 배송할 수 있습니다.

계산 도구 (Calculators)몰 농도 / 희석 / 분자량 / 단위 변환 / 생체 내 제형 / 용해도

g/mol

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