Autoimmunity

NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.

AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.

ONO-AE3-208 is an antagonist of the EP4 receptor (Ki = 1.3 nM) that less potently affects EP3, FP, and TP receptors (Kis = 30, 790, and 2,400 nM, respectively) and is without effect on other prostanoid receptors.

PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 μM).

Prednicarbate는 국소 코르티코스테로이드 제제입니다.

StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1, which specifically inhibits the IKKβ component of the IFN induction pathway.

Tetranactin is a macrotetrolide and a monovalent cation ionophore that has been found in S.

TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor.

(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP.

An alkaloid with anti-inflammatory activity

An S1P 1 receptor agonist

A neuropeptide with diverse biological activities

An inhibitor of PARP1 and 2

Artesunate-d4는 Artesunate로 표시된 중수소입니다. Artesunate는 STAT-3와 수출 단백질 1(EXP1)의 억제제입니다.

Balsalazide-d4는 Balsalazide로 표시된 중수소입니다.

Rofecoxib D5(MK 966 D5)는 Rofecoxib로 표시된 중수소입니다.

An internal standard for the quantification of chloroquine

A neuropeptide with diverse biological activities

Mitoxantrone-d8(mitozantrone-d8)은 Mitoxantrone이라고 표시된 중수소입니다. 미톡산트론은 토포이소머라제 II 억제제이며 또한 8.5μM의 IC50으로 단백질 키나제 C(PKC) 활성을 억제합니다.