TNF-α Antagonist (Synonyms: WP9QY) |
| Catalog No.GC45062 |
TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 199999-60-5
Sample solution is provided at 25 µL, 10mM.
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TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact site, this peptide interferes with both activating receptor activator of NF-κB (RANK) and TNF-α's recruitment and activation of osteoclasts. TNF-α antagonist has been used to block bone resorption in the study of systemic bone loss in rheumatoid arthritis and inflammatory bone destruction.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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