Reactive Oxygen Species
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Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.
ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Products Related to Reactive Oxygen Species(505)
- GC49372Kaempferol 7-neohesperidosideCAS: 17353-03-6Purity: >95.00%
A flavonoid glycoside with antioxidant and anticancer activities
- GC49420Gallic Acid-d2CAS: 294660-92-7Purity: >99.00%
An internal standard for the quantification of gallic acid
- GC49422PAR2 (1-6) amide (human) (trifluoroacetate salt)CAS: 2379569-17-0Purity: >95.00%
A peptide agonist of PAR2
- GC49426Taurine-d4CAS: 342611-14-7Purity: >99.00%
An internal standard for the quantification of taurine
- GC49436L-3-n-ButylphthalideCAS: 3413-15-8Purity: >99.00%
A phthalide with antiplatelet and neuroprotective activities
- GC49486Meglutol-d3CAS: 59060-36-5Purity: >99.00%
An internal standard for the quantification of meglutol
- GC49855Harmalol (hydrochloride hydrate)CAS: 6028-00-8Purity: >98.00%
A β-carboline alkaloid and an active metabolite of harmaline
- GC52027IsolariciresinolCAS: 548-29-8Purity: >98.00%
Isolariciresinol((+)-Cyclolariciresinol)은 류머티즘 연구에 사용할 수 있습니다.
- GC52073N-formyl-2-AminophenolCAS: 2843-27-8Purity: >98.00%
A bacterial secondary metabolite with antioxidant activity
- GC52190Imidazole Ketone ErastinCAS: 1801530-11-9Purity: >98.00%
Imidazole Ketone Erastin은 효과적이고 신진대사적으로 안정된 시스템 xc- 억제제 및 철사성 유도제이다.
- GC522275-(3',4'-Dihydroxyphenyl)-γ-ValerolactoneCAS: 21618-92-8Purity: >95.00%
An active metabolite of various polyphenols
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49372 | Kaempferol 7-neohesperidoside | 17353-03-6 | >95.00% | |
A flavonoid glycoside with antioxidant and anticancer activities | ||||
| GC49420 | Gallic Acid-d2 | 294660-92-7 | >99.00% | |
An internal standard for the quantification of gallic acid | ||||
| GC49422 | PAR2 (1-6) amide (human) (trifluoroacetate salt) | 2379569-17-0 | >95.00% | |
A peptide agonist of PAR2 | ||||
| GC49426 | Taurine-d4 | 342611-14-7 | >99.00% | |
An internal standard for the quantification of taurine | ||||
| GC49436 | L-3-n-Butylphthalide | 3413-15-8 | >99.00% | |
A phthalide with antiplatelet and neuroprotective activities | ||||
| GC49486 | Meglutol-d3 | 59060-36-5 | >99.00% | |
An internal standard for the quantification of meglutol | ||||
| GC49500 | Stobadine | 85202-17-1 | >98.00% | |
A pyridoindole antioxidant | ||||
| GC49521 | MHY553 | 6265-56-1 | >98.00% | |
An agonist of PPARα | ||||
| GC49557 | Cu-GTSM | 68341-14-0 | >95.00% | |
A copper-containing compound with diverse biological activities | ||||
| GC49560 | L6H21 | 24533-47-9 | >98.00% | |
Chalcone 유도체인 L6H21은 경구 활성, 강력하고 특이적인 골수 분화 2(MD-2) 억제제입니다. | ||||
| GC49597 | Leukotriene B4-d5 | - | >99.00% | |
An internal standard for the quantification of LTB 4 | ||||
| GC49708 | Biliverdin (technical grade) | 114-25-0 | >70.00% | |
A bile pigment | ||||
| GC49790 | Reuterin | 2134-29-4 | >98.00% | |
Reuterin은 그람 양성 및 그람 음성 박테리아뿐만 아니라 효모, 곰팡이 및 원생동물에 대해 활성인 광범위한 항균제입니다. | ||||
| GC49849 | 3-Aminosalicylic Acid | 570-23-0 | >98.00% | |
A salicylic acid derivative | ||||
| GC49855 | Harmalol (hydrochloride hydrate) | 6028-00-8 | >98.00% | |
A β-carboline alkaloid and an active metabolite of harmaline | ||||
| GC49864 | 6-Methylpterin | 708-75-8 | >98.00% | |
A derivative of folic acid | ||||
| GC49868 | D-α-Tocopheryl Quinone | 7559-04-8 | >98.00% | |
An oxidative metabolite of vitamin E | ||||
| GC52007 | N-hydroxylamine Dapsone | 32695-27-5 | >98.00% | |
An active metabolite of dapsone | ||||
| GC52027 | Isolariciresinol | 548-29-8 | >98.00% | |
Isolariciresinol((+)-Cyclolariciresinol)은 류머티즘 연구에 사용할 수 있습니다. | ||||
| GC52073 | N-formyl-2-Aminophenol | 2843-27-8 | >98.00% | |
A bacterial secondary metabolite with antioxidant activity | ||||
| GC52081 | Chamazulene | 529-05-5 | >98.00% | |
천연 화합물인 Chamazulene은 류코트리엔 B4 형성의 항산화제 유형 억제제입니다. | ||||
| GC52164 | Cu-ATSP | 68341-12-8 | >98.00% | |
ferroptotic 세포 사멸의 강력한 억제제인 \u200b\u200bCu-ATSP는 CuATSM보다 거의 20배 더 강력합니다. | ||||
| GC52190 | Imidazole Ketone Erastin | 1801530-11-9 | >98.00% | |
Imidazole Ketone Erastin은 효과적이고 신진대사적으로 안정된 시스템 xc- 억제제 및 철사성 유도제이다. | ||||
| GC52227 | 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone | 21618-92-8 | >95.00% | |
An active metabolite of various polyphenols | ||||