GLPBio

Phospholipase

Phospholipases are enzymes that catalyze the hydrolysis of phospholipids into fatty acids and other lipid mediators. It plays a variety of roles in tumorgenesis , inflammation and brain disorders etc.

Products Related to Phospholipase(136)

  • GC43670 structure
    GC43670FKGK 11
    CAS: 1071000-98-0
    Purity: >98.00%

    FKGK 11은 GVIA iPLA2(그룹 VIA 칼슘 비의존성 포스포리파제 A2)의 강력하고 선택적인 억제제입니다.

  • GC43671 structure
    GC43671FKGK 18
    CAS: 1071001-09-6
    Purity: >95.00%

    FKGK 18은 선택적 VIA 칼슘 비의존성 포스포리파제 A2(GVIA iPLA2) 억제제입니다.

  • GC43695 structure
    GC43695Folipastatin
    CAS: 139959-71-0
    Purity: >95.00%

    폴리파스타틴은 IC50이 39μM인 포스포리파제 A2의 강력한 억제제입니다.

  • GC43701 structure
    GC43701FTY720 phenoxy-biotin
    Purity: >95.00%

    FTY720은 면역 조절제로, 스핑고신-1-인산 (S1P) 수용체를 다운조절하며, 스핑고신 운반 단백질 ABCB1 및 르코트리엔 C4 운반 단백질 ABCC1의 활동을 증가시키고 세포소성 인지 A2 활동을 억제합니다.

  • GC43756 structure
    GC43756GK187
    CAS: 1071001-50-7
    Purity: >95.00%

    GK187은 XI(50) 값이 0.0001인 강력하고 선택적인 Group VIA 칼슘 비의존성 포스포리파제 A2(GVIA iPLA2) 억제제입니다.

  • GC43812 structure
    GC43812HEPC
    CAS: 60793-01-3
    Purity: >95.00%

    Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase activity.

  • GC43815 structure
    GC43815Heptanoyl thio-PC
    Purity: >98.00%

    Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity.

  • GC44222 structure
    GC44222ML-298
    CAS: 1426916-02-0
    Purity: >98.00%

    ML298은 355nM의 IC50을 갖는 포스포리파제 D2(PLD2)의 강력하고 선택적인 억제제입니다. ML298은 U87-MG 교모세포종 세포에서 침습적 이동을 감소시킵니다.

  • GC44223 structure
    GC44223ML-299
    CAS: 1426916-00-8
    Purity: >95.00%

    ML-299는 선택적 알로스테릭 조절제이자 포스포리파제 D1 및 D2의 이중 억제제입니다(IC50 값은 각각 6 및 12 nM임). ML-299는 U87-MG 교모세포종 세포에서 침습적 이동을 감소시킵니다.

  • GC44549 structure
    GC44549Palmitoyl thio-PC
    CAS: 113881-60-0
    Purity: >98.00%

    Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity.

  • GC44661 structure
    GC44661PLC thio-PIP2 (sodium salt)
    Purity: >98.00%

    Phospholipase C (PLC) catalyzes the hydrolysis of phosphatidylinositol (4,5) bisphosphate (PIP2) on the cytoplasmic side of the cell membrane to yield diacylglycerol and inositol-1,4,5-triphosphate (IP3).

  • GC44664 structure
    GC44664p-Nitrophenylphosphorylcholine
    CAS: 21064-69-7
    Purity: >99.50%

    p-Nitrophenylphosphorylcholine은 인공적으로 합성된 색소를 생성하는 기질로 인지질 분해효소 C와 관련된 인산디에스테라제 활성의 색소 검출에 일반적으로 사용된다.

  • GC44764 structure
    GC44764PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (ammonium salt)
    Purity: >98.00%

    The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids.

  • GC44794 structure
    GC44794Pyrrophenone
    CAS: 341973-06-6
    Purity: >99.50%

    피로페논은 IC50 값이 4.2nM인 강력하고 특이적인 세포질 포스포리파제 A2α(cPLA2α) 억제제입니다.

  • GC44943 structure
    GC44943sPLA2 Inhibitor
    CAS: 393569-31-8
    Purity: >95.00%

    D-티로신 유도체인 sPLA2 억제제는 인간 비췌장 분비 PLA2 동형 IIa(hnpsPLA2-IIa)에 대한 IC50이 29nM인 경구 활성, 강력한 분비 포스포리파제 A2(sPLA2) 억제제입니다.

  • GC45618 structure
    GC45618(±)-trans-GK563
    CAS: 2351820-19-2
    Purity: >94.00%

    A GVIA iPLA 2 inhibitor

  • GC45995 structure
    GC45995DO264
    CAS: 2301866-59-9
    Purity: >98.50%

    An ABHD12 inhibitor

  • GC46342 structure
    GC46342(R)-Bromoenol lactone-d7
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC46350 structure
    GC46350(S)-Bromoenol lactone-d7
    CAS: 478288-94-7
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC46352 structure
    GC46352(S)-DO271
    CAS: 2301865-01-8
    Purity: >98.00%

    An inactive control for DO264

  • GC46494 structure
    GC464941-Stearoyl-2-Arachidonoyl-d11-sn-glycero-3-PC
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC46761 structure
    GC467619-Oxononanoic Acid
    CAS: 2553-17-5
    Purity: >98.00%

    An oxidized fatty acid

  • GC46955 structure
    GC46955Bromoenol lactone-d7
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC47049 structure
    GC47049CAY10641
    CAS: 1233706-89-2
    Purity: >98.00%

    An inactive alcohol derivative of a highly potent cPLA 2 inhibitor