Metabolism
- Sterol Biosynthesis(26)
- PPAR(216)
- 5-alpha Reductase(9)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(8)
- Aminopeptidase(10)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(63)
- CETP(13)
- Cholesterol absorption(1)
- CPT1(3)
- CYP3A/CYP450(26)
- Dehydrogenase(139)
- DHFR(11)
- DGAT(13)
- Dopamine β-hydroxylase(14)
- Enolase(11)
- FAAH(40)
- Factor Xa(49)
- Ferroptosis(200)
- Folate Analogue(3)
- Glucokinase(17)
- HLE(1)
- HMG-CoA Reductase(39)
- HSP(77)
- IDO(52)
- KRAS-PDEδ(4)
- MAO(9)
- Metabolic Enzymes(0)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(17)
- P450(146)
- PDE(254)
- Phospholipase(117)
- Procollagen C Proteinase(2)
- Saccharometabolism(1)
- SCD(19)
- SGLT(31)
- TPH(6)
- Transferase(183)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(18)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(20)
- Glutathione Reductase(0)
- Thioredoxin Reductase(0)
- Catalase(8)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(47)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(98)
- Pyruvate kinase(9)
- Others(4)
- MGL(1)
- Galactosidase(6)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(12)
- Bile Acids & Microbiome(94)
- Bone Growth & Remodeling(35)
- Carbohydrate Metabolism(126)
- Cofactors & Vitamins(64)
- Dyslipidemias(73)
- Inborn Errors of Metabolism(80)
- Metabolic Syndrome(16)
- Necroptosis(10)
- Necrosis(15)
- Nutrient Sensing(12)
- Phosphodiesterase(27)
- Reproductive Biology(126)
- Thermogenesis(6)
- Prolyl Hydroxylation Enzymes(1)
- Biliary System(4)
- Metabolic Disease(4)
- Fat Mass and Obesity-associated Protein (FTO)(2)
- SHIP(1)
Products for Metabolism
- Cat.No. 상품명 정보
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GC66197
α-?Terpinyl acetate
α-Terpinyl acetate는 Laurus nobilis L. 정유에서 분리된 모노테르펜 에스테르입니다. 821d96072c2d58d8970e76f526b0f6b8α- 테르피닐 아세테이트는 Kd 값이 5.4μ인 P450 2B6의 활성 부위에 결합하는 경쟁적 P450 2B6 기질이며;M.821d96072c2d58d8970e76f526b0f6b8
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GC11123
α-CEHC
A major metabolite of δ-tocopherol
-
GC48276
α-Cyclodextrin (hydrate)
A cyclic hexasaccharide
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GC48278
α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
A bis-phosphorylated derivative of α-D-glucose
-
GC48279
α-D-Glucose-1-phosphate (sodium salt hydrate)
An intermediate in glycogen metabolism
-
GC52253
α-Enolase (1-19)-biotin Peptide
A biotinylated α-enolase peptide
-
GC45208
α-hydroxy Metoprolol
α-hydroxy Metoprolol is an active metabolite of the β1-adrenergic receptor blocker metoprolol.
-
GC45210
α-Linolenic Acid (sodium salt)
α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables.
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GC48283
α-Linolenic Acid-d14
An internal standard for the quantification of αLinolenic acid
-
GC45602
α-Linolenic Acid-d5 MaxSpec• Standard
-
GC49008
α-Muricholic Acid-d4
An internal standard for the quantification of α-muricholic acid
-
GC40480
α-Phenyl-α-(2-pyridyl)acetonitrile
α-Phenyl-α-(2-pyridyl)thioacetamide, also known as antigastrin and SC-15396, is an inhibitor of gastric acid secretion.
-
GC45232
β-D-Glucosamine Pentaacetate
β-D-Glucosamine pentaacetate is an N-acetylglucosamine derivative that has been shown to promote hyaluronic acid production.
-
GC49769
β-Glucogallin
A plant metabolite and an aldose reductase 2 inhibitor
-
GC49890
β-Glycerophosphate-d5 (sodium salt hydrate)
An internal standard for the quantification of β-glycerophosphate
-
GC49647
β-Hyodeoxycholic Acid (hydrate)
A 3β epimer of hyodeoxycholic acid
-
GC49007
β-Muricholic Acid-d4
An internal standard for the quantification of β-muricholic acid
-
GC41502
β-Myrcene
β-방향족 휘발성 화합물인 Myrcene(β-β-Myrcene)은 TNFα 유도 NF-κB 활성을 억제합니다.
-
GC40551
γ-CEHC
The major tocopherol obtained from natural dietary sources is γ-tocopherol, whereas α-tocopherol is the form of Vitamin E typically obtained from synthetic supplements.
-
GC52400
γ-Glu-Ala (trifluoroacetate salt)
A dipeptide
-
GC52404
γ-Glu-Phe (trifluoroacetate salt)
A dipeptide with metabolism-altering activity
-
GC45239
δ4-Abiraterone
δ4-Abiraterone은 abiraterone의 주요 대사 산물입니다. δ4-아비라테론은 CYP17A1, 3b-하이드록시스테로이드 탈수소효소(3βHSD) 및 스테로이드-5a-환원효소(SRD5A)의 억제제이자 안드로겐 수용체의 길항제입니다.
-
GC15975
α-Estradiol
&알파-에스트라디올은 약한 에스트로겐이며 안드로겐 탈모증 치료에서 국소 약물로 사용되는 환원효소 억제제입니다.
-
GC49009
ω-Muricholic Acid-d4
An internal standard for the quantification of ω-MCA
-
GC49296
τ-Fluvalinate
A pyrethroid acaricide
-
GC46314
(±)-β-Hydroxybutyrate-d4 (sodium salt)
An internal standard for the quantification of (±)βhydroxybutyrate
-
GC52010
(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid
An oxylipin gut microbiota metabolite
-
GC52013
(±)-10-hydroxy-12(Z)-Octadecenoic Acid
An oxylipin and metabolite of linoleic acid
-
GC52421
(±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5
An internal standard for the quantification of (±)-10-hydroxy-12(Z)-octadecenoic acid
-
GC41661
(±)-4-hydroxy Propranolol β-D-Glucuronide
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol.
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GC46284
(±)-Cotinine-d3
An internal standard for the quantification of cotinine
-
GC41671
(±)-Equol 4'-sulfate (sodium salt)
(±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.
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GC41315
(±)-Ketoprofen Glucuronide
(±)-Ketoprofen glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) ketoprofen.
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GC40954
(±)-N-3-Benzylnirvanol
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (-)-N-3-benzylnirvanol.
-
GC49875
(±)-N-desmethyl Venlafaxine (hydrochloride)
A minor active metabolite of venlafaxine
-
GC39271
(±)-Naringenin
(±)-나린제닌은 자연적으로 발생하는 플라보노이드입니다.
-
GC45618
(±)-trans-GK563
A GVIA iPLA2 inhibitor
-
GC40802
(±)12(13)-DiHOME
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.
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GC40270
(±)5(6)-DiHET
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
-
GC40282
(+)-5-trans Cloprostenol
Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses.
-
GC45260
(+)-Cloprostenol isopropyl ester
(+)-클로프로스테놀 이소프로필 에스테르, 프로스타글란딘 F2α 유사체는 (+)-클로프로스테놀의 중간체입니다.
-
GC45262
(+)-Cloprostenol methyl ester
(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α).
-
GC45264
(+)-Geodin
(+) - 곰팡이 대사 산물인 지오딘은 항균 활성을 나타냅니다.
-
GC12404
(+)-Ketoconazole
(+)-케토코나졸((+)-R 41400)은 이미다졸 항진균제인 CYP3A4 억제제입니다.
-
GC30424
(-)-Cephaeline dihydrochloride (NSC 32944)
(-)-Cephaeline dihydrochloride(NSC 32944)는 IC50이 121 μ인 선택적 CYP2D6 억제제입니다.
-
GC18343
(-)-CP 55,940
(-)-CP 55,940 is a potent and non-selective cannabinoid (CB) receptor agonist with Ki values of 0.5 to 5 and 0.69 to 2.8 nM for CB1 and CB2 receptors, respectively.
-
GC14049
(-)-Epigallocatechin gallate (EGCG)
다양한 생물학적 활동을 가진 페놀
-
GC45248
(-)-FINO2
(-)-FINO2는 강력한 ferroptosis 유도제입니다. (-)-FINO2는 GPX4 활성을 억제합니다. (-)-FINO2는 제1철을 산화시키는 안정한 산화제이며 다양한 pH 수준에서 안정합니다. (-)-FINO2는 광범위한 지질 과산화를 유발합니다.
-
GC14520
(-)-p-Bromotetramisole Oxalate
ALP 억제제, 강력하고 비특이적
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GC45252
(-)-Sitagliptin Carbamoyl Glucuronide
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
-
GC18622
(2'S)-Nicotine-1-oxide
(2'S)-Nicotine-1-oxide is a metabolite of nicotine .
-
GC41691
(2R)-Glycerol-O-β-D-galactopyranoside
(2R)-글리세롤-O-β-D-갈락토피라노시드(3-O-β-D-갈락토피라노실-sn-글리세롤)는 lac 오페론의 세 가지 성분 모두에 대한 좋은 기질입니다.
-
GC49690
(3R,5R)-Rosuvastatin (calcium salt)
A potential impurity found in bulk preparations of rosuvastatin
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GC41694
(3S)-hydroxy Quinidine
(3S)-hydroxy Quinidine is an active quinidine metabolite.
-
GC60396
(3S,5R)-Fluvastatin sodium
(3S,5R)-플루바스타틴 나트륨((3S,5R)-XU 62-320)은 플루바스타틴의 (3S,5R)-거울상 이성질체입니다.
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GC68317
(3S,5R)-Fluvastatin-d6 sodium
-
GC13751
(3S,5S)-Atorvastatin (sodium salt)
negetive control of Atorvastatin, HMG-CoA reductase inhibitor
-
GC46333
(4′-Hydroxy)phenoxybenzoic Acid
A pyrethroid insecticide metabolite
-
GC48508
(4-Carboxybutyl-d4)triphenylphosphonium (bromide)
An internal standard for the quantification of (4-carboxybutyl)triphenylphosphonium
-
GC41695
(6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride)
(6R,S)-5,6,7,8-Tetrahydrofolic acid (THFA), the reduced form of folic acid, serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism.
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GC41088
(6S)-Tetrahydrofolic Acid
(6S)-Tetrahydrofolic acid is a diastereomer of tetrahydrofolic acid, a reduced form of folic acid that serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism.
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GC34980
(E)-Ferulic acid
(E)-Ferulic acid는 식물 세포벽에 풍부한 방향족 화합물인 Ferrulic acid의 이성질체입니다. (E)-페룰린산은 β-카테닌의 인산화를 일으켜 β-카테닌의 프로테아좀 분해를 유발하고 pro-apoptotic factor Bax의 발현을 증가시키고 pro-survivin 인자 survivin의 발현을 감소시킨다. (E)-페룰산은 활성산소종(ROS)을 제거하고 지질 과산화를 억제하는 강력한 능력을 보여줍니다. (E)-Ferulic acid는 인간 폐암 세포주 H1299에서 항증식 및 항이동 효과를 모두 발휘합니다.
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GC40286
(E,Z)-2-propyl-2-Pentenoic Acid
(E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity.
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GC49189
(E/Z)-4-hydroxy Tamoxifen-d5
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen
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GA11210
(H-Cys-OH)2
-
GC34984
(R)-(-)-Rolipram
(R)-(-)-Rolipram은 Rolipram의 R-거울상 이성질체입니다.
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GC25001
(R)-Avanafil
R-Avanafil is a strong competitive inhibitor of phosphodiesterase 5 (PDE5) with a demonstrated in vitro IC 50 of 5.2 nM.
-
GC40678
(R)-Bromoenol lactone
(R)-브로모에놀 락톤((R)-BEL)은 칼슘 비의존성 포스포리파제 γ(iPLA2γ)의 비가역적 키랄 메커니즘 기반 억제제입니다.
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GC52290
(R)-HTS-3
An inhibitor of LPCAT3
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GC67864
(R)-Irsenontrine
-
GC41722
(R,S)-Carvedilol Glucuronide
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide.
-
GC61548
(Rac)-5-Keto Fluvastatin
(Rac)-5-Keto Fluvastatin(3-Hydroxy-5-Keto Fluvastatin)은 Fluvastatin(XU 62320)의 불순물입니다.
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GC62743
(Rac)-EC5026
(Rac)-EC5026((Rac)-BPN-19186)은 특허 WO2019156991A1(39페이지)에서 추출된 가용성 에폭사이드 가수분해효소(sEH)의 강력한 피페리딘 억제제이며 0.06 nM의 Ki를 갖는다.
-
GC69796
(Rac)-Etavopivat
(Rac)-Etavopivat((Rac)-FT-4202)는 Etavopivat 이성질체입니다. Etavopivat은 경구 효능을 가진 적혈구 아세트산 키나제-R (PKR) 활성화제로, 사랑모양 세포병 및 기타 혈색소 질환 연구에 사용될 수 있습니다.
-
GC61750
(Rac)-Indoximod
(Rac)-인독시모드(1-메틸-DL-트립토판)는 인돌아민 2,3-디옥시게나제(IDO) 억제제입니다.
-
GC46347
(S)-(+)-Methoprene
(S)-메토프렌은 유충 호르몬 유사체로 곤충이 번데기에서 성충으로 변하는 것을 막고 살충제로 사용됩니다.
-
GC40679
(S)-Bromoenol lactone
(S)-브로모에놀 락톤((S)-BEL)은 배양된 쥐 대동맥 평활근(A10)에서 아라키도네이트의 바소프레신 유도 방출을 억제하는 칼슘 비의존성 포스포리파제 A2β(iPLA2β)의 비가역적 키랄 메커니즘 기반 억제제입니다. IC50이 2μM인 세포.
-
GC50321
(S)-C33
(S)-C33은 IC50이 11nM인 강력하고 선택적인 PDE9(phosphodiesterase-9) 억제제입니다.
-
GC48719
(S)-Canadine
(S)-Canadine은 살충 활성이 있는 베르베린 생합성의 알칼로이드 및 중간체입니다.
-
GC46352
(S)-DO271
An inactive control for DO264
-
GC49520
(S)-Equol
(S)-Equol은 Ki가 0.73nM인 에스트로겐 수용체 β에 대한 고친화성 리간드입니다.
-
GC60417
(S)-Indoximod
(S)-인독시모드(1-메틸-L-트립토판)는 인돌아민 2,3-디옥시게나제(IDO)의 억제제입니다. (S)-Indoximod는 암 연구에 사용할 수 있습니다.
-
GC69891
(S)-Indoximod-d3
(S)-Indoximod-d3는 (S)-Indoximod의 데우테르화 물질입니다. (S)-Indoximod(1-Methyl-L-tryptophan)은 인돌아민-2,3-이중산화효소(IDO) 억제제입니다. (S)-Indoximod는 암 연구에 사용될 수 있습니다.
-
GC40145
(S)-Laudanosine
(S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium.
-
GC14486
(S)-Mephenytoin
(S)-메페니토인((+)-메페니토인)은 항경련제입니다.
-
GC49179
(S)-O-Desmethyl Naproxen
A metabolite of (S)-naproxen
-
GC18596
(±)-2-propyl-4-Pentenoic Acid
(±)-2-프로필-4-펜텐산(4-en-VPA)은 발프로산의 주요 독성 대사산물입니다.
-
GC49034
1(R)-(Trifluoromethyl)oleyl alcohol
An oleic acid analog
-
GC46365
1,1'-(Azodicarbonyl)dipiperidine
A Mitsunobu reagent
-
GC41762
1,2,3,5-Tetra-O-acetyl-D-xylofuranose
1,2,3,5-Tetra-O-acetyl-D-xylofuranose는 뉴클레오티드 합성의 원료입니다.
-
GC46040
1,2,3-Trielaidoyl-rac-glycerol
A triacylglycerol
-
GC45698
1,2,3-Triheptanoyl-rac-glycerol
1,2,3-Triheptanoyl-rac-glycerol(Propane-1,2,3-triyl triheptanoate)은 글리세롤에 세 개의 홀수 사슬 7-탄소(헵타노에이트) 지방산으로 구성된 합성 중쇄 트리글리세리드(MCT)입니다. 등뼈.
-
GC45285
1,2,3-Trihexanoyl-rac-glycerol
-
GC45956
1,2,3-Trinonanoyl-rac-glycerol
A triacylglycerol
-
GC46009
1,2,3-Trioctanoyl-rac-glycerol-13C3
An internal standard for the quantification of 1,2,3-trioctanoyl glycerol-13C3
-
GC46373
1,2,3-Triundecanoyl Glycerol
A triacylglycerol
-
GC41782
1,2-bis(heptanoylthio) Glycerophosphocholine
Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH).
-
GC40236
1,2-Dilinoleoyl-sn-glycerol
1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (18:2) side chains attached at both the sn-1 and sn-2 positions.
-
GC41808
1,2-Dioctanoyl PC
Phosphatidylcholine (PC) species are a common class of phospholipids that comprise the mammalian cell membrane.
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GC41837
1,3,7-Trimethyluric Acid
1,3,7-트리메틸요르산은 카페인의 대사산물입니다. 카페인에 대한 대사 비율 1,3,7-Trimethyluric Acid는 코호트에서 CYP3A 활성의 가변성을 설명하는 바이오마커로 평가될 수 있습니다.