RR6 |
| Catalog No.GC32740 |
RR6는 재조합된 바닌-1에 대한 IC50 값이 540 nM인 강력하고 선택적이며, 가역적이고 경쟁적으로 작용하는 구강 흡수 가능한 바닌 억제제입니다. RR6은 또한 인간, 소 및 쥐 혈청 판테테이나아제를 각각 40 nM, 41 nM 및 87 nM의 IC50 값을 가지고 강력하게 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1351758-37-6
Sample solution is provided at 25 µL, 10mM.
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RR6 is a selective, reversible, and competitive vanin inhibitor.target: vaninIn vivo: Oral administration of RR6 in rats completely inhibited plasma vanin activity and caused alterations of plasma lipid concentrations upon fasting, thereby illustrating its potential use in chemical biology research. RR6 at 3 mg/mL inrats caused a nearly complete inhibition of plasma vanin.
[1]. Jansen PA et al. Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease. ACS Chem Biol. 2013 Mar 15;8(3):530-4.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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