Thalidomide-NH-PEG7 |
| Catalog No.GC67500 |
탈리도마이드-NH-PEG7은 ADC용으로 합성된 E3 리간드-링커 접합체입니다. 821d96072c2d58d8970e76f526b0f6b8탈리도마이드-NH-PEG7은 링커에 의해 단백질의 리간드에 연결되어 매우 특이적인 PARP1 분해제인 PROTAC iRucaparib-AP6를 형성할 수 있습니다.821d96072c2d58d8970e76f526b0f6b8
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2641838-98-2
Sample solution is provided at 25 µL, 10mM.
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Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader[1].
[1]. Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation.Nat Chem Biol. 2019 Dec;15(12):1223-1231.
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