Thalidomide-propargyl |
| Catalog No.GC38862 |
Thalidomide-propargyl은 CRBN 단백질 모집에 사용되는 Thalidomide 기반 Cereblon 리간드입니다. 탈리도마이드-프로파길은 링커에 의해 단백질에 대한 리간드에 연결되어 PROTAC를 포함하는 IMiD를 형성할 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2098487-39-7
Sample solution is provided at 25 µL, 10mM.
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Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-propargyl can be connected to the ligand for protein by a linker to form the IMiD containing PROTACs[1].
[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.
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