GLPBio

TLR8 antagonist-1

Catalog No.: GC84265Purity:>99.50%
COASDSData Sheet
TLR8 antagonist-1 (Compound 10) is a selective TLR8 antagonist.

제품은 연구용으로만 사용됩니다. 인체에 사용할 수 없으며 환자에게 판매하지 않습니다.

TLR8 antagonist-1
Cas No.: 1111460-83-3
1mgIn Stock
$122.00
1
5mgIn Stock
$304.00
1
10mgIn Stock
$486.00
1
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제품 설명 (Description)

TLR8 antagonist-1 (Compound 10) is a selective TLR8 antagonist. TLR8 antagonist-1 can inhibit TLR8 -mediated inflammation and signaling pathways, reduce the recruitment of MyD88, and inhibit the NF-κB and IRF pathways. TLR8 antagonist-1 has anti-inflammatory activity [1].

References:
[1]. Matziol T, et al. Discovery of Novel Isoxazole-Based Small-Molecule Toll-Like Receptor 8 Antagonists. J Med Chem. 2025 Feb 27;68(4):4888-4907.

제품 문서 (Product Documents)

Purity:>99.50%Appearance:A solid
COASDSData Sheet

화학적 특성 (Chemical Properties)

CAS 번호
1111460-83-3
분자식
C21H29N3O4
분자량
387.47
용해도
DMSO: 100 mg/mL (258.08 mM; ultrasonic and warming and heat to 60°C)
보관
Store at -20°C
배송 조건
평가용 샘플은 아이스팩과 함께 배송됩니다. 그 외 용량은 실온 배송되며, 요청 시 아이스팩과 함께 배송할 수 있습니다.

계산 도구 (Calculators)몰 농도 / 희석 / 분자량 / 단위 변환 / 생체 내 제형 / 용해도

g/mol

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