L-Ornithine-1,2,3,4,5- 13 C 5 hydrochloride is the 13 C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is an orally active CaSR and p38 activator. L-Ornithine hydrochloride inhibits ROS and supports urea cycle function. L-Ornithine hydrochloride can be used to study kidney diseases involving proximal tubular cell damage caused by oxidative stress or crystallopathy, as well as research related to anxiety disorders [1] [2] [3].
References:
[1]. Shin S, et al. l-ornithine activates Ca signaling to exert its protective function on human proximal tubular cells. Cellular signalling. 2020 Mar;67:109484.
[2]. Demura S, et al. Effect of L-ornithine hydrochloride ingestion on intermittent maximal anaerobic cycle ergometer performance and fatigue recovery after exercise. European journal of applied physiology. 2011 Nov;111(11):2837-43.
[3]. Kurata K, et al. Orally administered L-ornithine elevates brain L-ornithine levels and has an anxiolytic-like effect in mice[J]. Nutritional Neuroscience, 2011, 14(6): 243-248.
References:
[1]. Shin S, et al. l-ornithine activates Ca signaling to exert its protective function on human proximal tubular cells. Cellular signalling. 2020 Mar;67:109484.
[2]. Demura S, et al. Effect of L-ornithine hydrochloride ingestion on intermittent maximal anaerobic cycle ergometer performance and fatigue recovery after exercise. European journal of applied physiology. 2011 Nov;111(11):2837-43.
[3]. Kurata K, et al. Orally administered L-ornithine elevates brain L-ornithine levels and has an anxiolytic-like effect in mice[J]. Nutritional Neuroscience, 2011, 14(6): 243-248.