Lipases

4-Nitrophenyl butyrate (4-NPB) is a colorimetric substrate for lipases.

1,2-Dilauroyl-rac-glycerol is a diacylglycerol that contains lauric acid at the sn-1 and sn-2 positions.

cis-Parinaric acid is a naturally occurring polyunsaturated fatty acid containing an unusual conjugated (Z,E,E,Z) tetraene.

MAGL Inhibitor Compound 23 is a potent, selective, reversible and competitive inhibitor of MAGL, with an IC50 of 80 nM. MAGL Inhibitor Compound 23 exhibits anti-proliferative effects against human breast, colorectal, and ovarian cancer cells. MAGL Inhibitor Compound 23 blocks MAGL in cell-based as well as in vivo assays.

URB754 is a potent and noncompetitive inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 200 nM for the recombinant rat brain enzyme.

Resorufin butyrate is a fluorogenic substrate for triglyceride lipases that is amenable to high-throughput analyses.

(R)-KT109 is the (R) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109.

(S)-KT109 is the (S) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109.

1,3-Didecanoyl-rac-glycerol is a saturated diacylglycerol with decanoic acid at the sn-1 and sn-3 positions.

2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the central cannabinoid (CB1) receptor.

The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2).

Endocannabinoids such as 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors.

In humans, two forms of diacylglycerol lipase, DAGLα and DAGLβ, generate the endocannabinoid 2-arachidonoyl glycerol by attacking DAG at the sn-1 position.

KT109 N2 regioisomer is an N2-carbamoylated regioisomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109.

In humans, two forms of diacylglycerol lipase, DAGLα and DAGLβ, generate the endocannabinoid 2-arachidonoyl glycerol by attacking DAG at the sn-1 position.

In humans, two forms of diacylglycerol lipase, DAGLα and DAGLβ, generate the endocannabinoid 2-arachidonoyl glycerol by attacking DAG at the sn-1 position.

1,2-Dipalmitoyl-3-Oleoyl-rac-glycerol, a major P-containing triacylglycerol, can be found in palm oil, palm stearin, cocoa butter, and lard.

A triacylglycerol

A colorimetric lipase and esterase substrate

An inhibitor of MAGL

An internal standard for the quantification of orlistat