Reactive O2/N2 Pathways

(±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

(±)14-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

(±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

(±)17-HDHA is an autoxidation product of docosahexaenoic acid in vitro.

(±)17-HDHA is an autoxidation product of docosahexaenoic acid in vitro.

(±)4-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

(±)7-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

(±)8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

Resolvins are a group of polyhydroxylated metabolites of docosahexaenoic acid (DHA) found in the inflammatory exudates of aspirin-treated experimental animals.

22-HDHA is an oxidation product of docosahexaenoic acid.

(±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

(±)11-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.

It has been reported that anandamide (AEA) can be used directly by cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases to produce ethanolamide congeners of the classical PGs, including PGF2α.

8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation.

8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans.

8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α of non-enzymatic origin.

8-iso PGF1α is an isoprostane that was first identified in human semen.

8-iso PGF1β is a potential autoxidation product of DGLA.

10-Nitrooleate (CXA-10), a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles.

15-deoxy-δ12,14-Prostaglandin J2 Glutathione (15-deoxy-δ12,14-PGJ2 Glutathione) is a non-enzymatic adduct formed from 15-deoxy-δ12,14-PGJ2 and glutathione.

1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes.

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.

4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress.

4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.