Sphingolipids
Products for Sphingolipids
- Cat.No. Product Name Information
- GC43071 C22 Sphingomyelin (d18:1/22:0) C22 Sphingomyelin is a naturally occurring form of sphingomyelin.
- GC43072 C23 Globotriaosylceramide (d18:1/23:0) C23 Globotriaosylceramide is a sphingolipid that has been used as a standard for the quantification of globotriaosylceramides in human fibroblasts by HPLC/APCI-MS.
- GC45836 C24 (2'(R)-hydroxy) dihydro Ceramide (d18:0/24:0) A hydroxylated dihydro ceramide
- GC45834 C24 (2'(R)-hydroxy) Phytoceramide (t18:0/24:0) A bioactive sphingolipid
- GC45835 C24 (2'(S)-hydroxy) Phytoceramide (t18:0/24:0) A sphingolipid
- GC46109 C24 1-Deoxyceramide (m18:1/24:0) A very long-chain atypical ceramide
- GC43073 C24 3'-sulfo Galactosylceramide (d18:1/24:0) C24 3'-sulfo Galactosylceramide is an endogenous sulfated glycolipid, which are also known as sulfatides.
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GC43074
C24 Ceramide (d18:1/24:0)
Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase.
- GC47005 C24 Ceramide-d7 (d18:1-d7/24:0) An internal standard for the quantification of lignoceric ceramide
- GC46110 C24 dihydro 1-Deoxyceramide (m18:0/24:0) A very long-chain atypical ceramide
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GC43075
C24 dihydro Ceramide (d18:0/24:0)
C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.
- GC43076 C24 Phytosphingosine (t18:0/24:0) C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis.
- GC46111 C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) A very long-chain atypical ceramide
- GC43077 C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) C24:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.
- GC43078 C24:1 Ceramide (d18:1/24:1(15Z)) Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase.
- GC47006 C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) An internal standard for the quantification of nervonic ceramide
- GC45952 C24:1 dihydro 1-Deoxyceramide (m18:0/24:1) A very long-chain atypical ceramide
- GC47007 C26 Sphingomyelin (d18:1/26:0) A sphingolipid
- GC47009 C26:1 Sphingomyelin (d18:1/26:1(17Z)) A naturally occurring sphingolipid
- GC43080 C30 Ceramide (d18:1/30:0) C30 Ceramide is a naturally occurring ceramide that has been found in the stratum corneum of human and nude mouse skin.
- GC43081 C30(ω-hydroxy) Ceramide (d18:1/30:0) C30(ω-hydroxy) Ceramide is a bioactive sphingolipid found in the stratum corneum layer of mammalian epidermis.
- GC43082 C32 Ceramide (d18:1/32:0) C32 Ceramide is a naturally occurring ceramide that has been found in the stratum corneum of human and nude mouse skin.
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GC43084
C4 Ceramide (d18:1/4:0)
C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC43086 C6 Biotin Ceramide (d18:1/6:0) C6 Ceramide-biotin is an affinity probe that allows C2 ceramide (d18:1/2:0) to be detected or immobilized through interaction with the biotin ligand.
- GC45839 C6 Biotin dihydro Ceramide (d18:0/6:0) An affinity probe for C6 dihydro ceramide binding partners
- GC49013 C6 Biotin Ganglioside GD3 (d18:1/6:0) (ammonium salt) An affinity probe for ganglioside GD3 binding partners
- GC43089 C6 Biotin Glucosylceramide (d18:1/6:0) C6 Biotin glucosylceramide is an affinity probe that allows C6 glucosylceramide to be detected or immobilized through interaction with the biotin ligand.
- GC45840 C6 Biotin Phytoceramide (t18:0/6:0) An affinity probe for C6 phytoceramide binding partners
- GC11079 C6 Ceramide (d18:1/6:0) C6-ceramide, a ceramide pathway activator, shows activity against a variety of cancer cell lines. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects.
- GC43091 C6 Ceramide (d18:1/6:0) Alkyne C6 Ceramide alkyne is an ω-alkyne derivative of C6 ceramide.
- GC40688 C6 D-threo Ceramide (d18:1/6:0) C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM).
- GC43092 C6 dihydro Ceramide (d18:0/6:0) C6 dihydro Ceramide is a metabolically inactive analog of C6 ceramide that has been used as a negative control in experiments investigating the biological activity of C6 ceramide.
- GC47015 C6 Glucosylceramide (d18:2/6:0) A glucosylated form of C6 ceramide
- GC40689 C6 L-erythro Ceramide (d18:1/6:0) C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC40690 C6 L-threo Ceramide (d18:1/6:0) C6 L-threo Ceramide (d18:1/6:0) is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC43096 C6 NBD Ceramide (d18:1/6:0) C6 NBD Ceramide (d18:1/6:0) is a Golgi apparatus fluorescent probe with cell membrane permeability.
- GC43097 C6 NBD dihydro Ceramide (d18:0/6:0) C6 NBD dihydro Ceramide (d18:0/6:0) is a sphinganine analog and can be used as fluorescent dye for labeling fatty acid.
- GC43098 C6 NBD Galactosylceramide (d18:1/6:0) C6 NBD galactosylceramide is an active derivative of galactosylceramide that is tagged with fluorescent C6 nitrobenzoxadiazole (C6 NBD).
- GC43099 C6 NBD Glucosylceramide (d18:1/6:0) C6 NBD Glucosylceramide (d18:1/6:0) is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm).
- GC43101 C6 NBD L-threo Ceramide (d18:1/6:0) C6 NBD L-threo Ceramide (d18:1/6:0) is a membrane-permeable ceramides.
- GC43100 C6 NBD Lactosylceramide (d18:1/6:0) C6 NBD Lactosylceramide (d18:1/6:0) is a derivative of lactosylceramides, and can be used in lactosylceramide synthase assay as a fluorescent acceptor substrate. C6 NBD Lactosylceramide (d18:1/6:0) can also be used in cancer research.
- GC40774 C6 NBD Phytoceramide (t18:0/6:0) C6 NBD phytoceramide is a biologically active derivative of C6 phytoceramide that is tagged with a fluorescent C6 nitrobenzoxadiazole group.
- GC43103 C6 NBD Sphingomyelin (d18:1/6:0) C6 NBD Sphingomyelin (d18:1/6:0) is a fluorescent short-chain analogue of Sphingomyelin.
- GC43104 C6 Phytoceramide (t18:0/6:0) C6 Phytoceramide is a cell-permeable analog of phytoceramide.
- GC45616 C6 Urea Ceramide An inhibitor of neutral ceramidase
- GC43106 C8 Ceramide-1-phosphate (d18:1/8:0) C8 ceramide-1-phosphate is a short-chain analog of the naturally occurring ceramide-1-phosphate.
- GC43107 C8 Ceramine (d18:1/8:0) C8 Ceramine is an analog of C8 ceramide in which the carbonyl group of the ceramide is replaced by a methylene group.
- GC43109 C8 D-threo Ceramide (d18:1/8:0) C8 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC43108 C8 dihydro Ceramide (d18:0/8:0) C8 dihydro Ceramide (d18:0/8:0) is a negative control of C8 Ceramide. C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. C8-Ceramide has anti-proliferation properties and acts as a potent chemotherapeutic agent. C8-Ceramide stimulates dendritic cells to promote T cell responses upon virus infections. C8-Ceramide induces slight activation of protein kinase (PKC) in vitro.
- GC43110 C8 Galactosylceramide (d18:1/8:0) C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids.
- GC43111 C8 L-threo Ceramide (d18:1/8:0) C8 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC43112 C8 Phytoceramide (t18:0/8:0) C8 Phytoceramide is a cell-permeable analog of phytosphingosine.
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GC18757
CAY10444
A family of related G-protein coupled receptors that bind sphingosine-1 phosphate (S1P) as a high-affinity ligand have recently been cloned.
- GC40757 CAY10734 An S1P1 receptor agonist
- GC41494 CAY10739 CAY10739 is a selective S1PR1 inhibitor, with a pIC50 of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4.
- GC52489 Ceramide (hydroxy) (bovine spinal cord) A sphingolipid
- GC52485 Ceramide (non-hydroxy) (bovine spinal cord) A sphingolipid
- GC52486 Ceramide Phosphoethanolamine (bovine) A sphingolipid
- GC43229 Ceramide Phosphoethanolamines (bovine) Ceramide phosphoethanolamine (CPE) is an analog of sphingomyelin that contains ethanolamine rather than choline as the head group.
- GC47073 Ceramides (hydroxy) A mixture of hydroxy fatty acid-containing ceramides
- GC43230 Ceramides (non-hydroxy) Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase.
- GC47074 Cerebroside C A fungal metabolite
- GC45877 CYM 5478 An S1P2 agonist
- GC40296 D-erythro-MAPP D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM).
- GC47189 D-erythro/L-threo Lysosphingomyelin (d18:1) A mixture of bioactive sphingolipids
- GC40792 D-threo Sphinganine (d18:0) D-threo Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and L-erythro sphinganine (d18:0).
- GC47276 D-threo-PPMP (hydrochloride) A GlyCer synthetase inhibitor
- GC49672 DL-erythro-PDMP (hydrochloride) A mixture of PDMP isomers
- GC43488 DL-erythro/threo Sphinganine (d16:0) DL-erythro/threo Sphinganine (d16:0) is a sphingolipid that is decreased in rats following long-term, low-dose administration of dimethoate and is used as a biomarker for dimethoate exposure.
- GC43494 DL-threo-PDMP (hydrochloride) DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP : D-threo (1R,2R) and L-threo (1S,2S) PDMP.
- GC47286 Eliglustat-d15 (tartrate) An internal standard for the quantification of eliglustat
- GC43615 EOS (d18:1/30:0/18:2) EOS is a ceramide found in the outer layer of the epidermis in mammals.
- GC43616 EOS (d18:1/32:1/18:2) EOS is a ceramide found in the outer layer of the epidermis in mammals.
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GC40887
FTY720 (R)-Phosphate
FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.
- GC52483 Fucosylated Ganglioside GM1 (porcine) (ammonium salt) A sphingolipid
- GC52288 Fumonisin B1-13C34 An internal standard for the quantification of fumonisin B1
- GC18469 Galactosylcerebrosides (bovine) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with hydroxy and non-hydroxy fatty acids.
- GC43721 Galactosylcerebrosides (hydroxy) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid.
- GC43722 Galactosylcerebrosides (non-hydroxy) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid.
- GC43723 Galactosylsphingosine (d18:1) Galactosylsphingosine (d18:1) (Galactosylsphingosine), a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease.
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GC43727
Ganglioside GD1a mixture (sodium salt)
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.
- GC43728 Ganglioside GD1b Mixture (sodium salt) Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit.
- GC49490 Ganglioside GD2 Mixture (bovine buttermilk) (ammonium salt) A semi-synthetic mixture of ganglioside GD2
- GC43729 Ganglioside GD3 Mixture (sodium salt) Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases.
- GC43730 Ganglioside GM1 Asialo Mixture Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase.
- GC47392 Ganglioside GM1 Mixture (ovine) (ammonium salt) A mixture of ganglioside GM1
- GC43731 Ganglioside GM2 Asialo Mixture Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2.
- GC40016 Ganglioside GM2 Mixture (sodium salt) Ganglioside GM2 is a glycosphingolipid component of cellular membranes, primarily the plasma membrane.
- GC43732 Ganglioside GM3 Mixture (sodium salt) Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation.
- GC52487 Ganglioside GM4 (chicken egg) (ammonium salt) A sphingolipid
- GC43734 Ganglioside GQ1b Mixture (sodium salt) Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit.
- GC52505 Ganglioside GT1b (bovine) (sodium salt) A sphingolipid
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GC43735
Ganglioside GT1b Mixture (sodium salt)
Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit.
- GC43757 Globotetraosylceramides (porcine RBC) Globotetraosylceramides are bioactive neutral glycosphingolipids.
- GC52492 Globotriaosylceramide (hydroxy) (porcine RBC) A sphingolipid
- GC52491 Globotriaosylceramide (non-hydroxy) (porcine RBC) A sphingolipid
- GC43758 Globotriaosylceramides (hydroxy) (porcine) Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides.
- GC43760 Globotriaosylceramides (porcine) Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides.
- GC18387 Glucocerebrosides Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.
- GC43768 Glucocerebrosides (Gaucher's spleen) Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.