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Sphingolipids

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  1. Cat.No. Product Name Information
  2. GC43071 C22 Sphingomyelin (d18:1/22:0) C22 Sphingomyelin is a naturally occurring form of sphingomyelin. C22 Sphingomyelin (d18:1/22:0)  Chemical Structure
  3. GC43072 C23 Globotriaosylceramide (d18:1/23:0) C23 Globotriaosylceramide is a sphingolipid that has been used as a standard for the quantification of globotriaosylceramides in human fibroblasts by HPLC/APCI-MS. C23 Globotriaosylceramide (d18:1/23:0)  Chemical Structure
  4. GC45836 C24 (2'(R)-hydroxy) dihydro Ceramide (d18:0/24:0) A hydroxylated dihydro ceramide C24 (2'(R)-hydroxy) dihydro Ceramide (d18:0/24:0)  Chemical Structure
  5. GC45834 C24 (2'(R)-hydroxy) Phytoceramide (t18:0/24:0) A bioactive sphingolipid C24 (2'(R)-hydroxy) Phytoceramide (t18:0/24:0)  Chemical Structure
  6. GC45835 C24 (2'(S)-hydroxy) Phytoceramide (t18:0/24:0) A sphingolipid C24 (2'(S)-hydroxy) Phytoceramide (t18:0/24:0)  Chemical Structure
  7. GC46109 C24 1-Deoxyceramide (m18:1/24:0) A very long-chain atypical ceramide C24 1-Deoxyceramide (m18:1/24:0)  Chemical Structure
  8. GC43073 C24 3'-sulfo Galactosylceramide (d18:1/24:0) C24 3'-sulfo Galactosylceramide is an endogenous sulfated glycolipid, which are also known as sulfatides. C24 3'-sulfo Galactosylceramide (d18:1/24:0)  Chemical Structure
  9. GC43074 C24 Ceramide (d18:1/24:0)

    Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase.

    C24 Ceramide (d18:1/24:0)  Chemical Structure
  10. GC47005 C24 Ceramide-d7 (d18:1-d7/24:0) An internal standard for the quantification of lignoceric ceramide C24 Ceramide-d7 (d18:1-d7/24:0)  Chemical Structure
  11. GC46110 C24 dihydro 1-Deoxyceramide (m18:0/24:0) A very long-chain atypical ceramide C24 dihydro 1-Deoxyceramide (m18:0/24:0)  Chemical Structure
  12. GC43075 C24 dihydro Ceramide (d18:0/24:0)

    C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.

    C24 dihydro Ceramide (d18:0/24:0)  Chemical Structure
  13. GC43076 C24 Phytosphingosine (t18:0/24:0) C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t18:0/24:0)  Chemical Structure
  14. GC46111 C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) A very long-chain atypical ceramide C24:1 1-Deoxyceramide (m18:1/24:1(15Z))  Chemical Structure
  15. GC43077 C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) C24:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))  Chemical Structure
  16. GC43078 C24:1 Ceramide (d18:1/24:1(15Z)) Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase. C24:1 Ceramide (d18:1/24:1(15Z))  Chemical Structure
  17. GC47006 C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) An internal standard for the quantification of nervonic ceramide C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z))  Chemical Structure
  18. GC45952 C24:1 dihydro 1-Deoxyceramide (m18:0/24:1) A very long-chain atypical ceramide C24:1 dihydro 1-Deoxyceramide (m18:0/24:1)  Chemical Structure
  19. GC47007 C26 Sphingomyelin (d18:1/26:0) A sphingolipid C26 Sphingomyelin (d18:1/26:0)  Chemical Structure
  20. GC47009 C26:1 Sphingomyelin (d18:1/26:1(17Z)) A naturally occurring sphingolipid C26:1 Sphingomyelin (d18:1/26:1(17Z))  Chemical Structure
  21. GC43080 C30 Ceramide (d18:1/30:0) C30 Ceramide is a naturally occurring ceramide that has been found in the stratum corneum of human and nude mouse skin. C30 Ceramide (d18:1/30:0)  Chemical Structure
  22. GC43081 C30(ω-hydroxy) Ceramide (d18:1/30:0) C30(ω-hydroxy) Ceramide is a bioactive sphingolipid found in the stratum corneum layer of mammalian epidermis. C30(ω-hydroxy) Ceramide (d18:1/30:0)  Chemical Structure
  23. GC43082 C32 Ceramide (d18:1/32:0) C32 Ceramide is a naturally occurring ceramide that has been found in the stratum corneum of human and nude mouse skin. C32 Ceramide (d18:1/32:0)  Chemical Structure
  24. GC43084 C4 Ceramide (d18:1/4:0)

    C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.

    C4 Ceramide (d18:1/4:0)  Chemical Structure
  25. GC43086 C6 Biotin Ceramide (d18:1/6:0) C6 Ceramide-biotin is an affinity probe that allows C2 ceramide (d18:1/2:0) to be detected or immobilized through interaction with the biotin ligand. C6 Biotin Ceramide (d18:1/6:0)  Chemical Structure
  26. GC45839 C6 Biotin dihydro Ceramide (d18:0/6:0) An affinity probe for C6 dihydro ceramide binding partners C6 Biotin dihydro Ceramide (d18:0/6:0)  Chemical Structure
  27. GC49013 C6 Biotin Ganglioside GD3 (d18:1/6:0) (ammonium salt) An affinity probe for ganglioside GD3 binding partners C6 Biotin Ganglioside GD3 (d18:1/6:0) (ammonium salt)  Chemical Structure
  28. GC43089 C6 Biotin Glucosylceramide (d18:1/6:0) C6 Biotin glucosylceramide is an affinity probe that allows C6 glucosylceramide to be detected or immobilized through interaction with the biotin ligand. C6 Biotin Glucosylceramide (d18:1/6:0)  Chemical Structure
  29. GC45840 C6 Biotin Phytoceramide (t18:0/6:0) An affinity probe for C6 phytoceramide binding partners C6 Biotin Phytoceramide (t18:0/6:0)  Chemical Structure
  30. GC11079 C6 Ceramide (d18:1/6:0) C6-ceramide, a ceramide pathway activator, shows activity against a variety of cancer cell lines. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects. C6 Ceramide (d18:1/6:0)  Chemical Structure
  31. GC43091 C6 Ceramide (d18:1/6:0) Alkyne C6 Ceramide alkyne is an ω-alkyne derivative of C6 ceramide. C6 Ceramide (d18:1/6:0) Alkyne  Chemical Structure
  32. GC40688 C6 D-threo Ceramide (d18:1/6:0) C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). C6 D-threo Ceramide (d18:1/6:0)  Chemical Structure
  33. GC43092 C6 dihydro Ceramide (d18:0/6:0) C6 dihydro Ceramide is a metabolically inactive analog of C6 ceramide that has been used as a negative control in experiments investigating the biological activity of C6 ceramide. C6 dihydro Ceramide (d18:0/6:0)  Chemical Structure
  34. GC47015 C6 Glucosylceramide (d18:2/6:0) A glucosylated form of C6 ceramide C6 Glucosylceramide (d18:2/6:0)  Chemical Structure
  35. GC40689 C6 L-erythro Ceramide (d18:1/6:0) C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. C6 L-erythro Ceramide (d18:1/6:0)  Chemical Structure
  36. GC40690 C6 L-threo Ceramide (d18:1/6:0) C6 L-threo Ceramide (d18:1/6:0) is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. C6 L-threo Ceramide (d18:1/6:0)  Chemical Structure
  37. GC43096 C6 NBD Ceramide (d18:1/6:0) C6 NBD Ceramide (d18:1/6:0) is a Golgi apparatus fluorescent probe with cell membrane permeability. C6 NBD Ceramide (d18:1/6:0)  Chemical Structure
  38. GC43097 C6 NBD dihydro Ceramide (d18:0/6:0) C6 NBD dihydro Ceramide (d18:0/6:0) is a sphinganine analog and can be used as fluorescent dye for labeling fatty acid. C6 NBD dihydro Ceramide (d18:0/6:0)  Chemical Structure
  39. GC43098 C6 NBD Galactosylceramide (d18:1/6:0) C6 NBD galactosylceramide is an active derivative of galactosylceramide that is tagged with fluorescent C6 nitrobenzoxadiazole (C6 NBD). C6 NBD Galactosylceramide (d18:1/6:0)  Chemical Structure
  40. GC43099 C6 NBD Glucosylceramide (d18:1/6:0) C6 NBD Glucosylceramide (d18:1/6:0) is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide (d18:1/6:0)  Chemical Structure
  41. GC43101 C6 NBD L-threo Ceramide (d18:1/6:0) C6 NBD L-threo Ceramide (d18:1/6:0) is a membrane-permeable ceramides. C6 NBD L-threo Ceramide (d18:1/6:0)  Chemical Structure
  42. GC43100 C6 NBD Lactosylceramide (d18:1/6:0) C6 NBD Lactosylceramide (d18:1/6:0) is a derivative of lactosylceramides, and can be used in lactosylceramide synthase assay as a fluorescent acceptor substrate. C6 NBD Lactosylceramide (d18:1/6:0) can also be used in cancer research. C6 NBD Lactosylceramide (d18:1/6:0)  Chemical Structure
  43. GC40774 C6 NBD Phytoceramide (t18:0/6:0) C6 NBD phytoceramide is a biologically active derivative of C6 phytoceramide that is tagged with a fluorescent C6 nitrobenzoxadiazole group. C6 NBD Phytoceramide (t18:0/6:0)  Chemical Structure
  44. GC43103 C6 NBD Sphingomyelin (d18:1/6:0) C6 NBD Sphingomyelin (d18:1/6:0) is a fluorescent short-chain analogue of Sphingomyelin. C6 NBD Sphingomyelin (d18:1/6:0)  Chemical Structure
  45. GC43104 C6 Phytoceramide (t18:0/6:0) C6 Phytoceramide is a cell-permeable analog of phytoceramide. C6 Phytoceramide (t18:0/6:0)  Chemical Structure
  46. GC45616 C6 Urea Ceramide An inhibitor of neutral ceramidase C6 Urea Ceramide  Chemical Structure
  47. GC43106 C8 Ceramide-1-phosphate (d18:1/8:0) C8 ceramide-1-phosphate is a short-chain analog of the naturally occurring ceramide-1-phosphate. C8 Ceramide-1-phosphate (d18:1/8:0)  Chemical Structure
  48. GC43107 C8 Ceramine (d18:1/8:0) C8 Ceramine is an analog of C8 ceramide in which the carbonyl group of the ceramide is replaced by a methylene group. C8 Ceramine (d18:1/8:0)  Chemical Structure
  49. GC43109 C8 D-threo Ceramide (d18:1/8:0) C8 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. C8 D-threo Ceramide (d18:1/8:0)  Chemical Structure
  50. GC43108 C8 dihydro Ceramide (d18:0/8:0) C8 dihydro Ceramide (d18:0/8:0) is a negative control of C8 Ceramide. C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. C8-Ceramide has anti-proliferation properties and acts as a potent chemotherapeutic agent. C8-Ceramide stimulates dendritic cells to promote T cell responses upon virus infections. C8-Ceramide induces slight activation of protein kinase (PKC) in vitro. C8 dihydro Ceramide (d18:0/8:0)  Chemical Structure
  51. GC43110 C8 Galactosylceramide (d18:1/8:0) C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. C8 Galactosylceramide (d18:1/8:0)  Chemical Structure
  52. GC43111 C8 L-threo Ceramide (d18:1/8:0) C8 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. C8 L-threo Ceramide (d18:1/8:0)  Chemical Structure
  53. GC43112 C8 Phytoceramide (t18:0/8:0) C8 Phytoceramide is a cell-permeable analog of phytosphingosine. C8 Phytoceramide (t18:0/8:0)  Chemical Structure
  54. GC18757 CAY10444

    A family of related G-protein coupled receptors that bind sphingosine-1 phosphate (S1P) as a high-affinity ligand have recently been cloned.

    CAY10444  Chemical Structure
  55. GC40757 CAY10734 An S1P1 receptor agonist CAY10734  Chemical Structure
  56. GC41494 CAY10739 CAY10739 is a selective S1PR1 inhibitor, with a pIC50 of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4. CAY10739  Chemical Structure
  57. GC52489 Ceramide (hydroxy) (bovine spinal cord) A sphingolipid Ceramide (hydroxy) (bovine spinal cord)  Chemical Structure
  58. GC52485 Ceramide (non-hydroxy) (bovine spinal cord) A sphingolipid Ceramide (non-hydroxy) (bovine spinal cord)  Chemical Structure
  59. GC52486 Ceramide Phosphoethanolamine (bovine) A sphingolipid Ceramide Phosphoethanolamine (bovine)  Chemical Structure
  60. GC43229 Ceramide Phosphoethanolamines (bovine) Ceramide phosphoethanolamine (CPE) is an analog of sphingomyelin that contains ethanolamine rather than choline as the head group. Ceramide Phosphoethanolamines (bovine)  Chemical Structure
  61. GC47073 Ceramides (hydroxy) A mixture of hydroxy fatty acid-containing ceramides Ceramides (hydroxy)  Chemical Structure
  62. GC43230 Ceramides (non-hydroxy) Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase. Ceramides (non-hydroxy)  Chemical Structure
  63. GC47074 Cerebroside C A fungal metabolite Cerebroside C  Chemical Structure
  64. GC45877 CYM 5478 An S1P2 agonist CYM 5478  Chemical Structure
  65. GC40296 D-erythro-MAPP D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). D-erythro-MAPP  Chemical Structure
  66. GC47189 D-erythro/L-threo Lysosphingomyelin (d18:1) A mixture of bioactive sphingolipids D-erythro/L-threo Lysosphingomyelin (d18:1)  Chemical Structure
  67. GC40792 D-threo Sphinganine (d18:0) D-threo Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and L-erythro sphinganine (d18:0). D-threo Sphinganine (d18:0)  Chemical Structure
  68. GC47276 D-threo-PPMP (hydrochloride) A GlyCer synthetase inhibitor D-threo-PPMP (hydrochloride)  Chemical Structure
  69. GC49672 DL-erythro-PDMP (hydrochloride) A mixture of PDMP isomers DL-erythro-PDMP (hydrochloride)  Chemical Structure
  70. GC43488 DL-erythro/threo Sphinganine (d16:0) DL-erythro/threo Sphinganine (d16:0) is a sphingolipid that is decreased in rats following long-term, low-dose administration of dimethoate and is used as a biomarker for dimethoate exposure. DL-erythro/threo Sphinganine (d16:0)  Chemical Structure
  71. GC43494 DL-threo-PDMP (hydrochloride) DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP : D-threo (1R,2R) and L-threo (1S,2S) PDMP. DL-threo-PDMP (hydrochloride)  Chemical Structure
  72. GC47286 Eliglustat-d15 (tartrate) An internal standard for the quantification of eliglustat Eliglustat-d15 (tartrate)  Chemical Structure
  73. GC43615 EOS (d18:1/30:0/18:2) EOS is a ceramide found in the outer layer of the epidermis in mammals. EOS (d18:1/30:0/18:2)  Chemical Structure
  74. GC43616 EOS (d18:1/32:1/18:2) EOS is a ceramide found in the outer layer of the epidermis in mammals. EOS (d18:1/32:1/18:2)  Chemical Structure
  75. GC40887 FTY720 (R)-Phosphate

    FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.

    FTY720 (R)-Phosphate  Chemical Structure
  76. GC52483 Fucosylated Ganglioside GM1 (porcine) (ammonium salt) A sphingolipid Fucosylated Ganglioside GM1 (porcine) (ammonium salt)  Chemical Structure
  77. GC52288 Fumonisin B1-13C34 An internal standard for the quantification of fumonisin B1 Fumonisin B1-13C34  Chemical Structure
  78. GC18469 Galactosylcerebrosides (bovine) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with hydroxy and non-hydroxy fatty acids. Galactosylcerebrosides (bovine)  Chemical Structure
  79. GC43721 Galactosylcerebrosides (hydroxy) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid. Galactosylcerebrosides (hydroxy)  Chemical Structure
  80. GC43722 Galactosylcerebrosides (non-hydroxy) Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid. Galactosylcerebrosides (non-hydroxy)  Chemical Structure
  81. GC43723 Galactosylsphingosine (d18:1) Galactosylsphingosine (d18:1) (Galactosylsphingosine), a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease. Galactosylsphingosine (d18:1)  Chemical Structure
  82. GC43727 Ganglioside GD1a mixture (sodium salt)

    Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.

    Ganglioside GD1a mixture (sodium salt)  Chemical Structure
  83. GC43728 Ganglioside GD1b Mixture (sodium salt) Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. Ganglioside GD1b Mixture (sodium salt)  Chemical Structure
  84. GC49490 Ganglioside GD2 Mixture (bovine buttermilk) (ammonium salt) A semi-synthetic mixture of ganglioside GD2 Ganglioside GD2 Mixture (bovine buttermilk) (ammonium salt)  Chemical Structure
  85. GC43729 Ganglioside GD3 Mixture (sodium salt) Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases. Ganglioside GD3 Mixture (sodium salt)  Chemical Structure
  86. GC43730 Ganglioside GM1 Asialo Mixture Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 Asialo Mixture  Chemical Structure
  87. GC47392 Ganglioside GM1 Mixture (ovine) (ammonium salt) A mixture of ganglioside GM1 Ganglioside GM1 Mixture (ovine) (ammonium salt)  Chemical Structure
  88. GC43731 Ganglioside GM2 Asialo Mixture Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Ganglioside GM2 Asialo Mixture  Chemical Structure
  89. GC40016 Ganglioside GM2 Mixture (sodium salt) Ganglioside GM2 is a glycosphingolipid component of cellular membranes, primarily the plasma membrane. Ganglioside GM2 Mixture (sodium salt)  Chemical Structure
  90. GC43732 Ganglioside GM3 Mixture (sodium salt) Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. Ganglioside GM3 Mixture (sodium salt)  Chemical Structure
  91. GC52487 Ganglioside GM4 (chicken egg) (ammonium salt) A sphingolipid Ganglioside GM4 (chicken egg) (ammonium salt)  Chemical Structure
  92. GC43734 Ganglioside GQ1b Mixture (sodium salt) Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit. Ganglioside GQ1b Mixture (sodium salt)  Chemical Structure
  93. GC52505 Ganglioside GT1b (bovine) (sodium salt) A sphingolipid Ganglioside GT1b (bovine) (sodium salt)  Chemical Structure
  94. GC43735 Ganglioside GT1b Mixture (sodium salt)

    Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit.

    Ganglioside GT1b Mixture (sodium salt)  Chemical Structure
  95. GC43757 Globotetraosylceramides (porcine RBC) Globotetraosylceramides are bioactive neutral glycosphingolipids. Globotetraosylceramides (porcine RBC)  Chemical Structure
  96. GC52492 Globotriaosylceramide (hydroxy) (porcine RBC) A sphingolipid Globotriaosylceramide (hydroxy) (porcine RBC)  Chemical Structure
  97. GC52491 Globotriaosylceramide (non-hydroxy) (porcine RBC) A sphingolipid Globotriaosylceramide (non-hydroxy) (porcine RBC)  Chemical Structure
  98. GC43758 Globotriaosylceramides (hydroxy) (porcine) Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides. Globotriaosylceramides (hydroxy) (porcine)  Chemical Structure
  99. GC43760 Globotriaosylceramides (porcine) Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides. Globotriaosylceramides (porcine)  Chemical Structure
  100. GC18387 Glucocerebrosides Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase. Glucocerebrosides  Chemical Structure
  101. GC43768 Glucocerebrosides (Gaucher's spleen) Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase. Glucocerebrosides (Gaucher's spleen)  Chemical Structure

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