GLPBio

Lydicamycin

Catalog No.: GC44098Purity:>95.00%Synonyms: Antibiotic CC 12
Lydicamycin is an antibiotic first isolated from Streptomyces.

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Lydicamycin
Cas No.: 133352-27-9
500μgIn Stock
$702.00
1

Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Lydicamycin is an antibiotic first isolated from Streptomyces. It is particularly cytotoxic against S. aureus, including the methicillin resistant 535 strain (MICs = 3.1-6.2 µg/ml). Lydicamycin also inhibits the growth of C. neoformans (MIC = 25 µg/ml) but is ineffective against Gram-negative bacteria.

Product Documents

Purity:>95.00%Appearance:A film

Chemical Properties

CAS No.
133352-27-9
Synonyms
Antibiotic CC 12
SMILES
OC1C(O)C2C(C(C(C3=C(O)CNC3=O)=O)(C)C(CCC(C)C(O)/C(C)=C/CC(/C=C/C(C)C(O)/C=C/CC(O)/C(C)=C/CC(CC4CCCN4C(N)=N)O)O)C(C)=C2)CC1
Molecular Formula
C47H74N4O10
Molecular Weight
855.1
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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