Lydicamycin is an antibiotic first isolated from Streptomyces. It is particularly cytotoxic against S. aureus, including the methicillin resistant 535 strain (MICs = 3.1-6.2 µg/ml). Lydicamycin also inhibits the growth of C. neoformans (MIC = 25 µg/ml) but is ineffective against Gram-negative bacteria.
Citations
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Product Documents
Purity:>95.00%Appearance:A film
Chemical Properties
CAS No.
133352-27-9
Synonyms
Antibiotic CC 12
SMILES
OC1C(O)C2C(C(C(C3=C(O)CNC3=O)=O)(C)C(CCC(C)C(O)/C(C)=C/CC(/C=C/C(C)C(O)/C=C/CC(O)/C(C)=C/CC(CC4CCCN4C(N)=N)O)O)C(C)=C2)CC1
Molecular Formula
C47H74N4O10
Molecular Weight
855.1
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
Reviews
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