GLPBio

MAO-B-IN-55

Catalog No.: GC79784Purity:>98.00%
MAO-B-IN-55 (Compound 5c) is a reversible competitive MAO-B inhibitor with an IC50 of 2.9 nM, and it exhibits approximately 2750-fold higher selectivity for MAO-B over MAO-A.

Products are for research use only. Not for human use. We do not sell to patients.


MAO-B-IN-55
Cas No.: 1458219-02-7
10mM (in 1mL DMSO)In Stock
$93.00
1
5mgIn Stock
$84.00
1
10mgIn Stock
$131.00
1
25mgIn Stock
$253.00
1
50mgIn Stock
$406.00
1

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

MAO-B-IN-55 (Compound 5c) is a reversible competitive MAO-B inhibitor with an IC50 of 2.9 nM, and it exhibits approximately 2750-fold higher selectivity for MAO-B over MAO-A. MAO-B-IN-55 can be used for the research of Parkinson's disease [1].

References:
[1]. Meiring L, Petzer JP, Petzer A. Inhibition of monoamine oxidase by 3,4-dihydro-2(1H)-quinolinone derivatives. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5498-502.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
1458219-02-7
Molecular Formula
C16H14BrNO2
Molecular Weight
332.2
Solubility
DMSO: ≥ 125 mg/mL (376.28 mM)
Storage
Store at 4°C, away from moisture
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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