Control analog of 6-bromoindirubin-3'-oxime. Displays minimal activity against CDK1/Cyclin B, GSK-3 α/β, and CDK5/p25 (IC50 values are 92.0, 44-100 and >100 μM respectively). Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nuc
MeBIO
Catalog No.: GC14967Purity:>98%Synonyms: Me6BIO, 1-Methyl-6-bromo-indirubin-3’-oxime
CDK/Cyclin/ GSK-3/p25/AhR agonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 667463-95-8
1mgIn Stock
$43.00
1
5mgIn Stock
$138.00
1
10mgIn Stock
$231.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $43.00 | In Stock | 1 | |
| 5mg | $138.00 | In Stock | 1 | |
| 10mg | $231.00 | In Stock | 1 |
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com
Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Chemical Properties
CAS No.
667463-95-8
Synonyms
Me6BIO, 1-Methyl-6-bromo-indirubin-3’-oxime
Chemical Name
6-bromo-3-[3-(hydroxyamino)indol-2-ylidene]-1-methylindol-2-one
SMILES
CN1C2=C(C=CC(=C2)Br)C(=C3C(=C4C=CC=CC4=N3)NO)C1=O
Molecular Formula
C17H12BrN3O2
Molecular Weight
370.2
Solubility
DMSO : 14.71 mg/mL (39.74 mM; ultrasonic and warming and heat to 60°C)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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