GLPBio

Misetionamide

Catalog No.: GC73133Purity:>99.00%Synonyms: GP-2250
Misetionamide is an orally oxathiazin-like compound.

Products are for research use only. Not for human use. We do not sell to patients.


Misetionamide
Cas No.: 856785-75-6
10mM (in 1mL DMSO)In Stock
$109.00
1
5 mgIn Stock
$99.00
1
10 mgIn Stock
$153.00
1
25 mgIn Stock
$306.00
1
50 mgIn Stock
$468.00
1

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Description

Misetionamide is an orally oxathiazin-like compound. Misetionamide is a glyceraldede-3-phosphate dedrogenase (GAPDH) inhibitor with antineoplastic activity. Misetionamide can be used for the research of cancer.

Misetionamide (OTD) (0-2000 μM; 0-72 h) induces cell death in TNBC cells[2].Misetionamide (OTD) (0-2000 μM; 12 h) inhibits TNBC cells proliferation[2].Misetionamide (OTD) (0-1000 μM; 18 h) induces necrosis and apoptosis in TNBC cells[2].Misetionamide (OTD) (250-1000 μM; 18 h) induces cell death by a ROS-dependent mechanism in TNBC cells[2].

References:
[1]. International Nonproprietary Names for Pharmaceutical Substances (INN). WHO Drug Information. 2022. 36(2):337. [2]. Jinih M, et al. Evaluation of the Cytotoxic Effects of the Novel Antineoplastic Agent 1,4,5-Oxathiazinane-4,4-dioxide on Triple Negative Breast Cancer Cells. Anticancer Res. 2021 May;41(5):2247-2256.

Product Documents

Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
856785-75-6
Synonyms
GP-2250
Molecular Formula
C3H7NO3S
Molecular Weight
137.16
Solubility
DMSO : 100 mg/mL (729.08 mM; Need ultrasonic)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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