Nilutamide is a non-steroidal antiandrogen that is an antagonist of the androgen receptor. It reverses testosterone-induced increases in cell proliferation with an IC50 value of 412 nM in mouse mammary carcinoma cells in vitro. It has antiandrogenic activity in both intact and castrated rats, inhibiting testosterone propionate-induced prostate growth when administered at a dose of 2.5 mg/kg. Formulations containing nilutamide have been used in combination with surgical castration in the treatment of metastatic prostate cancer.
Nilutamide
Catalog No.: GC44405Purity:>98.00%Synonyms: RU-23908
Nilutamide is a non-steroidal antiandrogen that is an antagonist of the androgen receptor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 63612-50-0
500mgIn Stock
$61.00
1
1gIn Stock
$115.00
1
5gIn Stock
$544.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 500mg | $61.00 | In Stock | 1 | |
| 1g | $115.00 | In Stock | 1 | |
| 5g | $544.00 | In Stock | 1 |
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com
Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
63612-50-0
Synonyms
RU-23908
SMILES
O=C1N(C2=CC(C(F)(F)F)=C([N+]([O-])=O)C=C2)C(C(C)(C)N1)=O
Molecular Formula
C12H10F3N3O4
Molecular Weight
317.2
Solubility
Chloroform: slightly soluble,DMSO: 25mM,Ethanol: 25mM,Methanol: slightly soluble
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
Reviews
Review for Nilutamide
Rating: 5
- 5 Star100%
- 4 Star0%
- 3 Star0%
- 2 Star0%
- 1 Star0%