GLPBio

Androgen Receptor

AR (androgen receptor) is a member of steroid hormone receptor and ligand-activated transcription factor. It plays a crucial role in prostate cellular proliferation and male sexual differentiation.

Products Related to Androgen Receptor(159)

  • GC13362 structure
    GC13362TOK-001
    CAS: 851983-85-2
    Purity: >99.50%

    TOK-001 (TOK-001) is a multifunctional antiandrogen and CYP17 inhibitor (IC50=47 nM) in castration resistant prostate cancer (CRPC).

  • GC13971 structure
    GC13971Cyproterone Acetate
    CAS: 427-51-0
    Purity: >98.00%

    Androgen receptor antagonist

  • GC27918 structure
    GC27918LX1
    CAS: 2647877-84-5
    Purity: >99.00%

    LX1 is an anti-prostate cancer compound that targets androgen receptor (AR), AR variants and steroidogenic enzyme AKR1C3.

  • GC10372 structure
    GC10372AZD3514
    CAS: 1240299-33-5
    Purity: >99.00%

    Androgen receptor downregulator

  • GC10547 structure
    GC10547ASC-J9
    CAS: 52328-98-0
    Purity: >98.00%

    A selective enhancer of AR degradation

  • GC10567 structure
    GC10567TCPOBOP
    CAS: 76150-91-9
    Purity: >98.00%

    TCPOBOP is a constitutive androgen receptor (CAR) agonist (EC 50 =0.05μM) that induces hepatocyte proliferation and hepatomegaly in mice without causing liver damage.

  • GC10618 structure
    GC10618Fluoxymesterone
    CAS: 76-43-7
    Purity: >98%

    Fluoxymesterone is a synthetic androgen drug that decomposes slowly in the body and has a long-lasting effect.

  • GC10785 structure
    GC10785Danazol
    CAS: 17230-88-5
    Purity: >98.00%

    Danazol is a synthetic anabolic steroid with properties of inhibition of interleukin-1 and TNF-α production.

  • GC11070 structure
    GC11070Dehydroepiandrosterone (DHEA)
    CAS: 53-43-0
    Purity: >98.00%

    Dehydroepiandrosterone (DHEA) and its sulfate ester, DHEAS, together represent the most abundant steroid hormones in the human body .

  • GC11386 structure
    GC11386ODM-201
    CAS: 1297538-32-9
    Purity: >99.00%

    ODM-201 is a potent antagonist of the androgen receptor (AR) with a Ki value of 11nM and an IC 50 value of 26nM.

  • GC11837 structure
    GC11837MI-136
    CAS: 1628316-74-4
    Purity: >98.50%

    menin-MLL interaction inhibitor

  • GC11957 structure
    GC11957RD162
    CAS: 915087-27-3
    Purity: >98%

    androgen receptor (AR) antagonist

  • GC12271 structure
    GC12271Bicalutamide
    CAS: 90357-06-5
    Purity: >98.00%

    Bicalutamide is a non-steroidal antiandrogen that selectively and competitively blocks androgen binding to the androgen receptor (AR), exerting anti-androgenic effects in peripheral tissues.

  • GC12385 structure
    GC12385MDV3100 (Enzalutamide)
    CAS: 915087-33-1
    Purity: >99.50%

    MDV3100 (Enzalutamide) is an oral inhibitor of androgen receptor (AR) with an IC 50 value of 36nM.

  • GC12445 structure
    GC12445TFM-4AS-1
    CAS: 188589-61-9
    Purity: >98%

    androgen receptor modulator

  • GC12791 structure
    GC127913,3'-Diindolylmethane
    CAS: 1968-05-4
    Purity: >98.00%

    A phytochemical with antiradiation and chemopreventative effects

  • GC12933 structure
    GC12933RU 58841
    CAS: 154992-24-2
    Purity: >99.50%

    A non-steroidal antiandrogen

  • GC12938 structure
    GC12938PF 998425
    CAS: 1076225-27-8
    Purity: >98.00%

    non-steroidal androgen receptor (AR) antagonist

  • GC12974 structure
    GC12974Medroxyprogesterone acetate
    CAS: 71-58-9
    Purity: >99.50%

    Medroxyprogesterone acetate (MPA) is a synthetic progestin.

  • GC13685 structure
    GC13685Andarine
    CAS: 401900-40-1
    Purity: >99.50%

    Andarine (S-4) is an orally active and selective nonsteroidal androgen receptor (AR) modulator (SARM) and a partial agonist, with Ki of 4 nM. Andarine (S-4) is identified as SARMs with potent and tissue-selective in vivo pharmacological activity.

  • GC14221 structure
    GC14221HE-3235
    CAS: 183387-50-0
    Purity: >98%

    HE-3235, synthetic analogue of 3β-androstanediol, is an orally bioavailable anticancer agent. HE-3235 is active in rodent models of prostate and breast cancer.

  • GC14560 structure
    GC14560Cl-4AS-1
    CAS: 188589-66-4
    Purity: >98%

    steroidal androgen receptor agonist

  • GC15774 structure
    GC157745α-dihydro-11-keto Testosterone
    CAS: 32694-37-4
    Purity: >98.00%

    5α-dihydro-11-keto Testosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione.

  • GC16631 structure
    GC16631EPI-001
    CAS: 227947-06-0
    Purity: >98.00%

    AR antagonist