NITD-2 |
Catalog No.GC64559 |
NITD-2, a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation.
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Cas No.: 1197896-79-9
Sample solution is provided at 25 µL, 10mM.
NITD-2, a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly[1].
NITD-2 inhibits de novo RNA synthesis[1].NITD-2 exhibited no antiviral activity in cell culture resulted from the poor cell penetratration[1].
[1]. Pornwaratt Niyomrattanakit, et al. Inhibition of dengue virus polymerase by blocking of the RNA tunnel. J Virol. 2010 Jun;84(11):5678-86.
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