P-gp
P-gp (P-glycoprotein) is a ATP-binding cassette transproters which overepxressed in multidrug-resistance cancer cells. It functions in pumping drug out of cell and lower intracellular drug concentration.
Products Related to P-gp(10)
- GC10928Tariquidar methanesulfonate, hydrateCAS: 625375-83-9Purity: >98.00%
A P-glycoprotein inhibitor
- GC10964Estradiol 17-(β-D-Glucuronide) (sodium salt)CAS: 15087-02-2Purity: >95.00%
Estradiol 17-(β-D-Glucuronide) is a metabolic product of estradiol, the main female sex hormone.
- GC15570TariquidarCAS: 206873-63-4Purity: >98.50%
Tariquidar is a potent and selective inhibitor of P-glycoprotein (P-gp) with a K D value of 5.1nM.
- GC15795Rhodamine 123 (chloride)CAS: 62669-70-9Purity: >99.00%
Rhodamine 123 (chloride) is a cell-permeable cationic fluorescent probe that specifically recognizes mitochondrial membrane potential, with maximum excitation/emission light of 507/529nm.
- GC16609LY335979 (Zosuquidar 3HCL)CAS: 167465-36-3Purity: >99.50%
Zosuquidar (LY335979) trihydrochloride is a P-glycoprotein (P-gp) inhibitor (Ki=59 nM). LY335979 (Zosuquidar 3HCL) shows anti-tumor activities, and can be used in acute myelogenous leukemia (AML) research.
- GC16672ZosuquidarCAS: 167354-41-8Purity: >98.00%
Zosuquidar is a novel and potent P-glycoprotein (P-gp; K i =59nM) inhibitor and multidrug resistance (MDR) modulator.
- GC17065Estradiol 3-(β-D-Glucuronide) (sodium salt)CAS: 14982-12-8Purity: >95.00%
substrate for multidrug resistance protein 2 (MRP2)
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC10391 | Hypophyllanthin | 33676-00-5 | >98.00% | |
P-glycoprotein (P-gp) inhibitor | ||||
| GC10928 | Tariquidar methanesulfonate, hydrate | 625375-83-9 | >98.00% | |
A P-glycoprotein inhibitor | ||||
| GC10964 | Estradiol 17-(β-D-Glucuronide) (sodium salt) | 15087-02-2 | >95.00% | |
Estradiol 17-(β-D-Glucuronide) is a metabolic product of estradiol, the main female sex hormone. | ||||
| GC15570 | Tariquidar | 206873-63-4 | >98.50% | |
Tariquidar is a potent and selective inhibitor of P-glycoprotein (P-gp) with a K D value of 5.1nM. | ||||
| GC15795 | Rhodamine 123 (chloride) | 62669-70-9 | >99.00% | |
Rhodamine 123 (chloride) is a cell-permeable cationic fluorescent probe that specifically recognizes mitochondrial membrane potential, with maximum excitation/emission light of 507/529nm. | ||||
| GC16609 | LY335979 (Zosuquidar 3HCL) | 167465-36-3 | >99.50% | |
Zosuquidar (LY335979) trihydrochloride is a P-glycoprotein (P-gp) inhibitor (Ki=59 nM). LY335979 (Zosuquidar 3HCL) shows anti-tumor activities, and can be used in acute myelogenous leukemia (AML) research. | ||||
| GC16672 | Zosuquidar | 167354-41-8 | >98.00% | |
Zosuquidar is a novel and potent P-glycoprotein (P-gp; K i =59nM) inhibitor and multidrug resistance (MDR) modulator. | ||||
| GC17065 | Estradiol 3-(β-D-Glucuronide) (sodium salt) | 14982-12-8 | >95.00% | |
substrate for multidrug resistance protein 2 (MRP2) | ||||
| GC25405 | Evodine | 6989-38-4 | >98% | |
Evodine, a natural product extracted from Evodiae fructus (EF), is a biomarker for quality assessment of EF in the Chinese Pharmacopoeia. Evodine is a potent P-gp inhibitor. | ||||
| GC13375 | Dofequidar fumarate | 153653-30-6 | >98.00% | |
MDR reversal agent | ||||