p97
p97 is a AAA-type ATPase that involved in mitosis-related events, such as golgi stacks fragmentation, tER formation, spindle pole body function and homotypic membrane fusion etc.
Products Related to p97(12)
- GC60257MSC1094308CAS: 2219320-08-6Purity: >98.00%
MSC1094308 is a non-competitive and reversible VPS4B/p97 (VCP) (I/II type AAA ATPase) allosteric inhibitor, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively. MSC1094308 inhibits the D2 ATPase activity by binding to a drugable hotspot of p97. MSC1094308 can be used in study of cancer.
- GC64694UPCDC-30245CAS: 1883351-01-6Purity: >99.50%
UPCDC-30245 is an allosteric p97 inhibitor with an IC50 of approximately 27 nM. UPCDC-30245 inhibits the p97 mutant N660K similar to wild type (WT; IC50=300 nM) and shows 3-fold resistance for p97 mutant T688A. UPCDC-30245 can be used in the research of cancer.
- GC71429VCP Activator 1Purity: >99.50%
VCP Activator 1 is a VCP activator that dose-dependently stimulates VCP ATPase activity.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC10048 | MNS | 1485-00-3 | >98% | |
Inhibitor of Src/Syk tyrosine kinases | ||||
| GC10824 | DBeQ | 177355-84-9 | >99.50% | |
P97 ATPase inhibitor | ||||
| GC17250 | NMS-873 | 1418013-75-8 | >99.50% | |
VCP/p97 inhibitor,selective and allosteric | ||||
| GC20117 | CB-5339 | 1863952-15-1 | >98.00% | |
CB-5339 is a potent and selective, orally bioavailable small molecule inhibitor of valosin containing protein (VCP)/p97, with an IC 50 value of 9nM. | ||||
| GC11749 | ML241 | 1346528-06-0 | >98% | |
p97 ATPase inhibitor | ||||
| GC13656 | ML241 hydrochloride | 2070015-13-1 | >99.50% | |
p97 ATPase inhibitor | ||||
| GC14059 | ML 240 | 1346527-98-7 | >99.50% | |
ATP-competitive inhibitor of p97 ATPase | ||||
| GC16351 | CB-5083 | 1542705-92-9 | >99.50% | |
CB-5083 is a highly selective and orally bioavailable AAA-ATPase p97 inhibitor with an IC 50 value of 11nM . | ||||
| GC32874 | NMS-859 | 1449236-96-7 | >98% | |
NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively. | ||||
| GC60257 | MSC1094308 | 2219320-08-6 | >98.00% | |
MSC1094308 is a non-competitive and reversible VPS4B/p97 (VCP) (I/II type AAA ATPase) allosteric inhibitor, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively. MSC1094308 inhibits the D2 ATPase activity by binding to a drugable hotspot of p97. MSC1094308 can be used in study of cancer. | ||||
| GC64694 | UPCDC-30245 | 1883351-01-6 | >99.50% | |
UPCDC-30245 is an allosteric p97 inhibitor with an IC50 of approximately 27 nM. UPCDC-30245 inhibits the p97 mutant N660K similar to wild type (WT; IC50=300 nM) and shows 3-fold resistance for p97 mutant T688A. UPCDC-30245 can be used in the research of cancer. | ||||
| GC71429 | VCP Activator 1 | - | >99.50% | |
VCP Activator 1 is a VCP activator that dose-dependently stimulates VCP ATPase activity. | ||||
