GLPBio

p97

p97 is a AAA-type ATPase that involved in mitosis-related events, such as golgi stacks fragmentation, tER formation, spindle pole body function and homotypic membrane fusion etc.

Products Related to p97(12)

  • GC10048 structure
    GC10048MNS
    CAS: 1485-00-3
    Purity: >98%

    Inhibitor of Src/Syk tyrosine kinases

  • GC10824 structure
    GC10824DBeQ
    CAS: 177355-84-9
    Purity: >99.50%

    P97 ATPase inhibitor

  • GC17250 structure
    GC17250NMS-873
    CAS: 1418013-75-8
    Purity: >99.50%

    VCP/p97 inhibitor,selective and allosteric

  • GC20117 structure
    GC20117CB-5339
    CAS: 1863952-15-1
    Purity: >98.00%

    CB-5339 is a potent and selective, orally bioavailable small molecule inhibitor of valosin containing protein (VCP)/p97, with an IC 50 value of 9nM.

  • GC11749 structure
    GC11749ML241
    CAS: 1346528-06-0
    Purity: >98%

    p97 ATPase inhibitor

  • GC13656 structure
    GC13656ML241 hydrochloride
    CAS: 2070015-13-1
    Purity: >99.50%

    p97 ATPase inhibitor

  • GC14059 structure
    GC14059ML 240
    CAS: 1346527-98-7
    Purity: >99.50%

    ATP-competitive inhibitor of p97 ATPase

  • GC16351 structure
    GC16351CB-5083
    CAS: 1542705-92-9
    Purity: >99.50%

    CB-5083 is a highly selective and orally bioavailable AAA-ATPase p97 inhibitor with an IC 50 value of 11nM .

  • GC32874 structure
    GC32874NMS-859
    CAS: 1449236-96-7
    Purity: >98%

    NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.

  • GC60257 structure
    GC60257MSC1094308
    CAS: 2219320-08-6
    Purity: >98.00%

    MSC1094308 is a non-competitive and reversible VPS4B/p97 (VCP) (I/II type AAA ATPase) allosteric inhibitor, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively. MSC1094308 inhibits the D2 ATPase activity by binding to a drugable hotspot of p97. MSC1094308 can be used in study of cancer.

  • GC64694 structure
    GC64694UPCDC-30245
    CAS: 1883351-01-6
    Purity: >99.50%

    UPCDC-30245 is an allosteric p97 inhibitor with an IC50 of approximately 27 nM. UPCDC-30245 inhibits the p97 mutant N660K similar to wild type (WT; IC50=300 nM) and shows 3-fold resistance for p97 mutant T688A. UPCDC-30245 can be used in the research of cancer.

  • GC71429 structure
    GC71429VCP Activator 1
    Purity: >99.50%

    VCP Activator 1 is a VCP activator that dose-dependently stimulates VCP ATPase activity.