GLPBio

Pomalidomide-C6-O-C5-O-C4-COOH

Catalog No.: GC73164Purity:>98.00%
Pomalidomide-C6-O-C5-O-C4-COOH is a E3 ligase ligand-linker conjugate comprising a Pomalidomide -based cereblon ligand and linker.

Products are for research use only. Not for human use. We do not sell to patients.


Pomalidomide-C6-O-C5-O-C4-COOH
Cas No.: 2375774-54-0
1 mgIn Stock
$132.00
1
5 mgIn Stock
$290.00
1
10 mgIn Stock
$464.00
1

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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

Pomalidomide-C6-O-C5-O-C4-COOH is a E3 ligase ligand-linker conjugate comprising a Pomalidomide -based cereblon ligand and linker. Pomalidomide-C6-O-C5-O-C4-COOH can be used for the synthesis of PROTACs.

References:
[1]. Steinebach C , et al. PROTAC-mediated crosstalk between E3 ligases. Chem Commun (Camb). 2019 Feb 5;55(12):1821-1824.

Product Documents

Purity:>98.00%Appearance:An oil

Chemical Properties

CAS No.
2375774-54-0
Molecular Formula
C29H41N3O8
Molecular Weight
559.65
Solubility
DMSO : 100 mg/mL (178.68 mM; ultrasonic and warming and heat to 60°C)
Storage
-20°C, sealed storage, away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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