Protein Oxidation

S-Nitrosylation reactions regulate protein function and mediate nitrosative stress.

Redox-sensitive cysteine residues in proteins may function as sensors of reactive oxygen species (ROS) and also serve as molecular switches, activating or deactivating proteins, following a change in oxidation state.

The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall.

10-Nitrooleate (CXA-10), a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles.

3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response.

3-Bromotyrosine-13C9,15N is intended for use as an internal standard for the quantification of 3-bromotyrosine by GC- or LC-MS.

Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis.

DAz-2 is a cell-permeable chemical probe used to detect cysteine oxidation in proteins.

Formed in vivo by the reaction of NO with superoxide

A fluorescent probe for sulfenic acid-containing proteins

A neuropeptide with diverse biological activities

A disulfide with diverse biological activities

A disulfide with diverse biological activities

A pyridoindole antioxidant

An intermediate in arginine and proline metabolism

A co-inducer of heat shock proteins