Proteolysis

The cleavage of the chromogenic caspase-3 substrate Ac-DEVD-pNA can be monitored at 405 nm.

H-D-Pro-Phe-Arg-pNA . 2 HCl is a chromogenic peptide substrate that has been used for the determination of kallikreins.

Z-RGR-pNA is a chromogenic substrate for the determination of factor Xa.

Ac-VDVAD-AFC is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer.

A caspase-3 fluorogenic substrate

Selective inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1)

MMP-3 inhibitor is a peptide inhibitor of matrix metalloproteinase-3 (MMP-3) with a Ki value of 95 nM.

Ac-LEHD-AMC (trifluoroacetate salt) is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm).

Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases u-calpain (calpain-1; IC50 = 7.5 nM) and m-calpain (calpain-2; IC50 = 78 nM).

4-Epianhydrochlortetracycline is a derivative of tetracycline .

Mca-DEVDAPK(Dnp)-OH is a fluorogenic substrate for caspase-3.

Dabcyl-YVADAPV-EDANS is a fluorogenic substrate for caspase-1.

A serine protease inhibitor

Suc-AAP-Abu-pNA is a chromogenic peptide substrate for pancreatic elastase.

MMP-8 Inhibitor I is a potent matrix metalloproteinase-8 (MMP-8) inhibitor with low oral bioavailability.

An inhibitor of palmitoyl protein thioesterase-1

Ginsenoside CK, a secondary ginsenoside biotransformed from major ginsenosides, is more bioavailable and soluble than its parent ginsenosides and holds great significance.

Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

Ac-AAVALLPAVLLALLAP-IETD-CHO is a composite of Ac-IETD-CHO, a peptide inhibitor of caspase-8, and a cell-permeable hydrophobic sequence derived from K-FGF.

Z-YVADLD-FMK is a peptide that contains the amino acid sequence YVAD, which is the cleavage site for caspase-1 and -4.

Mca-LEVDGW-K(Dnp)-NH2 is a fluorogenic substrate for caspase-4.

(Z-DEVD)2-Rh 110 is a fluorogenic substrate for caspase-3.

Ac-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO, a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF.

Ac-AAVALLPAVLLALLAP-VAD-CHO is a composite of Ac-VAD-CHO, a non-selective caspase inhibitor, and a cell-permeable hydrophobic sequence derived from K-FGF.